Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

4K2J

Decameric ring structure of KSHV (HHV-8) latency-associated nuclear antigen (LANA) DNA binding domain

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003677	molecular_function	DNA binding
A	0042025	cellular_component	host cell nucleus
B	0003677	molecular_function	DNA binding
B	0042025	cellular_component	host cell nucleus
C	0003677	molecular_function	DNA binding
C	0042025	cellular_component	host cell nucleus
D	0003677	molecular_function	DNA binding
D	0042025	cellular_component	host cell nucleus
E	0003677	molecular_function	DNA binding
E	0042025	cellular_component	host cell nucleus
F	0003677	molecular_function	DNA binding
F	0042025	cellular_component	host cell nucleus
G	0003677	molecular_function	DNA binding
G	0042025	cellular_component	host cell nucleus
H	0003677	molecular_function	DNA binding
H	0042025	cellular_component	host cell nucleus
I	0003677	molecular_function	DNA binding
I	0042025	cellular_component	host cell nucleus
J	0003677	molecular_function	DNA binding
J	0042025	cellular_component	host cell nucleus

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE FMT A 1201

Chain	Residue
A	SER1086
A	TYR1103
A	HOH1310
A	HOH1312
B	SER1086
B	TYR1103

site_id	AC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CL A 1202

Chain	Residue
A	HOH1333
A	ARG1119
A	ALA1129
A	GLY1130

site_id	AC3
Number of Residues	3
Details	BINDING SITE FOR RESIDUE CL A 1203

Chain	Residue
A	GLN1116
A	ILE1136
B	LYS1141

site_id	AC4
Number of Residues	3
Details	BINDING SITE FOR RESIDUE CL B 1201

Chain	Residue
A	LYS1141
B	GLN1116
B	ILE1136

site_id	AC5
Number of Residues	3
Details	BINDING SITE FOR RESIDUE CL B 1202

Chain	Residue
B	ARG1048
B	TRP1054
B	GLN1107

site_id	AC6
Number of Residues	5
Details	BINDING SITE FOR RESIDUE FMT C 1201

Chain	Residue
C	SER1086
C	TYR1103
C	HOH1302
C	HOH1318
D	SER1086

site_id	AC7
Number of Residues	7
Details	BINDING SITE FOR RESIDUE FMT C 1202

Chain	Residue
C	LYS1070
C	TRP1122
C	ALA1129
C	HOH1303
C	HOH1339
C	HOH1346
H	LEU1128

site_id	AC8
Number of Residues	3
Details	BINDING SITE FOR RESIDUE CL C 1203

Chain	Residue
C	GLN1116
C	ILE1136
D	LYS1141

site_id	AC9
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CL C 1204

Chain	Residue
C	ARG1048
C	TRP1054
C	GLN1107
C	THR1146
C	HOH1325

site_id	BC1
Number of Residues	3
Details	BINDING SITE FOR RESIDUE CL D 1201

Chain	Residue
C	LYS1141
D	GLN1116
D	ILE1136

site_id	BC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE FMT E 1201

Chain	Residue
E	SER1086
E	TYR1103
E	HOH1305
F	SER1086
F	HOH1303

site_id	BC3
Number of Residues	7
Details	BINDING SITE FOR RESIDUE FMT E 1202

Chain	Residue
E	GLY1067
E	LYS1070
E	ARG1119
E	ALA1129
E	GLY1130
E	CL1206
E	HOH1358

site_id	BC4
Number of Residues	3
Details	BINDING SITE FOR RESIDUE CL E 1203

Chain	Residue
E	GLN1116
E	ILE1136
F	LYS1140

site_id	BC5
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CL E 1204

Chain	Residue
E	PRO1084
E	VAL1085
E	HOH1336
F	HOH1334

site_id	BC6
Number of Residues	3
Details	BINDING SITE FOR RESIDUE CL E 1205

Chain	Residue
E	HIS1126
E	PRO1127
E	LEU1128

site_id	BC7
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CL E 1206

Chain	Residue
E	GLN1034
E	GLY1067
E	LYS1070
E	ARG1119
E	FMT1202

site_id	BC8
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CL F 1201

Chain	Residue
E	LYS1141
F	GLN1116
F	ILE1136
F	HOH1335

site_id	BC9
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CL F 1202

Chain	Residue
F	PRO1018
F	VAL1019
F	GLN1073
F	HOH1337

site_id	CC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CL F 1203

Chain	Residue
F	ARG1119
F	ALA1129
F	GLY1130
F	HOH1331

site_id	CC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE FMT G 1201

Chain	Residue
G	SER1086
G	TYR1103
G	HOH1313
H	SER1086
H	TYR1103
H	HOH1301

site_id	CC3
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CL G 1202

Chain	Residue
G	GLN1116
G	ILE1136
H	LYS1140
H	LYS1141
H	HOH1333

site_id	CC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CL H 1201

Chain	Residue
G	LYS1140
G	LYS1141
H	GLN1116
H	ILE1136

site_id	CC5
Number of Residues	3
Details	BINDING SITE FOR RESIDUE CL H 1202

Chain	Residue
H	ARG1048
H	TRP1054
H	THR1146

site_id	CC6
Number of Residues	3
Details	BINDING SITE FOR RESIDUE CL H 1203

Chain	Residue
H	ARG1119
H	GLY1130
H	HOH1321

site_id	CC7
Number of Residues	3
Details	BINDING SITE FOR RESIDUE FMT I 1201

Chain	Residue
I	GLN1034
I	LYS1070
I	TRP1122

site_id	CC8
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CL I 1202

Chain	Residue
I	LYS1141
J	GLN1116
J	ILE1136
J	HOH1323

site_id	CC9
Number of Residues	3
Details	BINDING SITE FOR RESIDUE CL I 1203

Chain	Residue
I	GLN1116
I	ILE1136
J	LYS1140

site_id	DC1
Number of Residues	3
Details	BINDING SITE FOR RESIDUE CL I 1204

Chain	Residue
I	ARG1048
I	LYS1081
J	PRO1093

site_id	DC2
Number of Residues	3
Details	BINDING SITE FOR RESIDUE CL I 1205

Chain	Residue
I	HIS1126
I	PRO1127
I	LEU1128

site_id	DC3
Number of Residues	5
Details	BINDING SITE FOR RESIDUE FMT J 1201

Chain	Residue
I	SER1086
J	SER1086
J	TYR1103
J	HOH1304
J	HOH1311

site_id	DC4
Number of Residues	6
Details	BINDING SITE FOR RESIDUE FMT J 1202

Chain	Residue
J	GLY1067
J	LYS1070
J	ARG1119
J	ALA1129
J	GLY1130
J	HOH1320

site_id	DC5
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CL J 1203

Chain	Residue
I	TYR1066
J	HIS1011
J	ARG1013
J	TYR1014
J	HOH1337

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)