4K1X
Ferredoxin-NADP(H) Reductase mutant with Ala 266 replaced by Tyr (A266Y) and residues 267-272 deleted.
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0004324 | molecular_function | ferredoxin-NADP+ reductase activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0034599 | biological_process | cellular response to oxidative stress |
| A | 0042167 | biological_process | heme catabolic process |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0004324 | molecular_function | ferredoxin-NADP+ reductase activity |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0034599 | biological_process | cellular response to oxidative stress |
| B | 0042167 | biological_process | heme catabolic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 24 |
| Details | BINDING SITE FOR RESIDUE FAD A 301 |
| Chain | Residue |
| A | PHE49 |
| A | GLY87 |
| A | PRO88 |
| A | LEU89 |
| A | THR90 |
| A | THR130 |
| A | ALA133 |
| A | GLU264 |
| A | TYR266 |
| A | HOH408 |
| A | HOH415 |
| A | ARG64 |
| A | HOH418 |
| A | HOH438 |
| A | HOH503 |
| A | HOH504 |
| B | ARG259 |
| A | ALA65 |
| A | TYR66 |
| A | SER67 |
| A | TYR80 |
| A | SER81 |
| A | ILE82 |
| A | VAL84 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 A 302 |
| Chain | Residue |
| A | GLN19 |
| A | PRO39 |
| A | GLN40 |
| A | ARG251 |
| site_id | AC3 |
| Number of Residues | 21 |
| Details | BINDING SITE FOR RESIDUE FAD B 301 |
| Chain | Residue |
| B | PHE49 |
| B | ARG64 |
| B | ALA65 |
| B | TYR66 |
| B | SER67 |
| B | TYR80 |
| B | SER81 |
| B | ILE82 |
| B | VAL84 |
| B | GLY87 |
| B | PRO88 |
| B | LEU89 |
| B | THR90 |
| B | THR130 |
| B | ALA133 |
| B | GLU215 |
| B | GLU264 |
| B | TYR266 |
| B | HOH404 |
| B | HOH463 |
| B | HOH508 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 16 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"16128574","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"18973834","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"24016470","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 10 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"18973834","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
