Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003677 | molecular_function | DNA binding |
| A | 0003906 | molecular_function | DNA-(apurinic or apyrimidinic site) endonuclease activity |
| A | 0004518 | molecular_function | nuclease activity |
| A | 0004519 | molecular_function | endonuclease activity |
| A | 0005829 | cellular_component | cytosol |
| A | 0006281 | biological_process | DNA repair |
| A | 0006284 | biological_process | base-excision repair |
| A | 0006974 | biological_process | DNA damage response |
| A | 0008081 | molecular_function | phosphoric diester hydrolase activity |
| A | 0008270 | molecular_function | zinc ion binding |
| A | 0008296 | molecular_function | 3'-5'-DNA exonuclease activity |
| A | 0008833 | molecular_function | deoxyribonuclease IV (phage-T4-induced) activity |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0016791 | molecular_function | phosphatase activity |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0003677 | molecular_function | DNA binding |
| B | 0003906 | molecular_function | DNA-(apurinic or apyrimidinic site) endonuclease activity |
| B | 0004518 | molecular_function | nuclease activity |
| B | 0004519 | molecular_function | endonuclease activity |
| B | 0005829 | cellular_component | cytosol |
| B | 0006281 | biological_process | DNA repair |
| B | 0006284 | biological_process | base-excision repair |
| B | 0006974 | biological_process | DNA damage response |
| B | 0008081 | molecular_function | phosphoric diester hydrolase activity |
| B | 0008270 | molecular_function | zinc ion binding |
| B | 0008296 | molecular_function | 3'-5'-DNA exonuclease activity |
| B | 0008833 | molecular_function | deoxyribonuclease IV (phage-T4-induced) activity |
| B | 0016787 | molecular_function | hydrolase activity |
| B | 0016791 | molecular_function | phosphatase activity |
| B | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ZN A 301 |
| Chain | Residue |
| A | GLU145 |
| A | ASP179 |
| A | HIS216 |
| A | GLU261 |
| A | HOH508 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ZN A 302 |
| Chain | Residue |
| E | DC306 |
| A | HIS182 |
| A | ASP229 |
| A | HIS231 |
| E | DC305 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN A 303 |
| Chain | Residue |
| A | ASP251 |
| A | ASP254 |
| A | HOH401 |
| B | ASP89 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE PEG A 304 |
| Chain | Residue |
| A | ALA204 |
| A | ARG205 |
| A | THR206 |
| A | VAL207 |
| A | LYS210 |
| B | GLN138 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ZN B 301 |
| Chain | Residue |
| B | GLU145 |
| B | ASP179 |
| B | HIS216 |
| B | GLU261 |
| B | HOH471 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN B 302 |
| Chain | Residue |
| B | HIS182 |
| B | ASP229 |
| B | HIS231 |
| M | DC306 |
| site_id | AC7 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE PEG B 303 |
| Chain | Residue |
| B | ALA204 |
| B | ARG205 |
| B | VAL207 |
| B | LYS210 |
Functional Information from PROSITE/UniProt
| site_id | PS00730 |
| Number of Residues | 8 |
| Details | AP_NUCLEASE_F2_2 AP endonucleases family 2 signature 2. GVCIDTCH |
| Chain | Residue | Details |
| A | GLY175-HIS182 | |
| site_id | PS00731 |
| Number of Residues | 17 |
| Details | AP_NUCLEASE_F2_3 AP endonucleases family 2 signature 3. MHlNDAkstfGsrvDrH |
| Chain | Residue | Details |
| A | MET215-HIS231 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 18 |
| Details | Binding site: {} |
Catalytic Information from CSA
| site_id | MCSA1 |
| Number of Residues | 11 |
| Details | M-CSA 11 |
| Chain | Residue | Details |
| A | ARG37 | transition state stabiliser |
| A | HIS231 | metal ligand |
| A | GLU261 | metal ligand |
| A | ALA69 | metal ligand |
| A | TYR72 | transition state stabiliser |
| A | HIS109 | metal ligand |
| A | GLU145 | metal ligand |
| A | ASP179 | metal ligand |
| A | HIS182 | metal ligand |
| A | HIS216 | metal ligand |
| A | ASP229 | metal ligand |
| site_id | MCSA2 |
| Number of Residues | 11 |
| Details | M-CSA 11 |
| Chain | Residue | Details |
| B | ARG37 | transition state stabiliser |
| B | HIS231 | metal ligand |
| B | GLU261 | metal ligand |
| B | ALA69 | metal ligand |
| B | TYR72 | transition state stabiliser |
| B | HIS109 | metal ligand |
| B | GLU145 | metal ligand |
| B | ASP179 | metal ligand |
| B | HIS182 | metal ligand |
| B | HIS216 | metal ligand |
| B | ASP229 | metal ligand |
