Functional Information from GO Data
Chain | GOid | namespace | contents |
H | 0004252 | molecular_function | serine-type endopeptidase activity |
H | 0006508 | biological_process | proteolysis |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 17 |
Details | BINDING SITE FOR RESIDUE 1NJ H 301 |
Chain | Residue |
H | HIS57 |
H | GLY219 |
H | GLY226 |
H | 1NJ302 |
H | SO4306 |
H | GOL309 |
H | HOH583 |
H | HOH594 |
H | HOH595 |
H | ASP189 |
H | SER190 |
H | LYS192 |
H | GLY193 |
H | SER195 |
H | SER214 |
H | TRP215 |
H | GLY216 |
site_id | AC2 |
Number of Residues | 19 |
Details | BINDING SITE FOR RESIDUE 1NJ H 302 |
Chain | Residue |
H | PRO246 |
H | ARG247 |
H | PRO248 |
H | 1NJ301 |
H | SO4304 |
H | SO4306 |
H | HOH527 |
H | HOH579 |
H | HOH602 |
H | HOH645 |
H | HOH650 |
L | SER119 |
L | LEU120 |
L | LEU121 |
L | THR128 |
L | PRO129 |
L | THR130 |
L | GLU132 |
L | HOH335 |
site_id | AC3 |
Number of Residues | 2 |
Details | BINDING SITE FOR RESIDUE CA H 303 |
Chain | Residue |
H | ARG84 |
H | HIS109 |
site_id | AC4 |
Number of Residues | 11 |
Details | BINDING SITE FOR RESIDUE SO4 H 304 |
Chain | Residue |
H | GLN143 |
H | ARG147 |
H | LYS192 |
H | ARG247 |
H | 1NJ302 |
H | SO4306 |
H | HOH503 |
H | HOH533 |
H | HOH561 |
H | HOH595 |
H | HOH602 |
site_id | AC5 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE SO4 H 305 |
Chain | Residue |
H | MET164 |
H | THR165 |
H | ARG230 |
H | HOH570 |
site_id | AC6 |
Number of Residues | 7 |
Details | BINDING SITE FOR RESIDUE SO4 H 306 |
Chain | Residue |
H | LYS192 |
H | 1NJ301 |
H | 1NJ302 |
H | SO4304 |
H | HOH479 |
H | HOH563 |
H | HOH598 |
site_id | AC7 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE SO4 H 307 |
Chain | Residue |
H | THR98 |
H | THR99 |
H | PRO170 |
H | HOH520 |
H | HOH548 |
site_id | AC8 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE SO4 H 308 |
Chain | Residue |
H | GLN81 |
H | SER82 |
H | ARG83 |
H | HOH562 |
site_id | AC9 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE GOL H 309 |
Chain | Residue |
H | LEU41 |
H | HIS57 |
H | 1NJ301 |
H | HOH590 |
H | HOH598 |
H | HOH626 |
site_id | BC1 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE SO4 L 201 |
Chain | Residue |
H | ARG129 |
L | CYS91 |
L | CYS102 |
L | ASP104 |
Functional Information from PROSITE/UniProt
site_id | PS00134 |
Number of Residues | 6 |
Details | TRYPSIN_HIS Serine proteases, trypsin family, histidine active site. VSAAHC |
Chain | Residue | Details |
H | VAL53-CYS58 | |
site_id | PS00135 |
Number of Residues | 12 |
Details | TRYPSIN_SER Serine proteases, trypsin family, serine active site. DSckGDSGGPHA |
Chain | Residue | Details |
H | ASP189-ALA200 | |
site_id | PS01186 |
Number of Residues | 16 |
Details | EGF_2 EGF-like domain signature 2. CrCheGYslladgvsC |
Chain | Residue | Details |
L | CYS112-CYS127 | |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 3 |
Details | ACT_SITE: Charge relay system => ECO:0000250 |
Chain | Residue | Details |
H | HIS57 | |
H | ASP102 | |
H | SER195 | |
site_id | SWS_FT_FI2 |
Number of Residues | 1 |
Details | BINDING: BINDING => ECO:0000250 |
Chain | Residue | Details |
H | ASP189 | |
Chain | Residue | Details |
H | ASN175 | |