4JYF

X-ray snapshots of possible intermediates in the time course of synthesis and degradation of protein-bound Fe4S4 clusters.

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003824	molecular_function	catalytic activity
A	0016491	molecular_function	oxidoreductase activity
A	0016740	molecular_function	transferase activity
A	0042364	biological_process	water-soluble vitamin biosynthetic process
A	0044272	biological_process	sulfur compound biosynthetic process
A	0046872	molecular_function	metal ion binding
A	0051536	molecular_function	iron-sulfur cluster binding
A	0051537	molecular_function	2 iron, 2 sulfur cluster binding
A	0051539	molecular_function	4 iron, 4 sulfur cluster binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SF4 A 401

Chain	Residue
A	CYS63
A	CYS67
A	CYS70
A	SAH402

---

site_id	AC2
Number of Residues	19
Details	BINDING SITE FOR RESIDUE SAH A 402

Chain	Residue
A	ARG180
A	MET199
A	PRO229
A	ILE231
A	TYR303
A	LEU305
A	TYR306
A	SF4401
A	HOH511
A	HOH517
A	HOH519
A	HOH528
A	HOH567
A	HOH808
A	TYR69
A	SER108
A	SER136
A	ARG159
A	GLU161

---

site_id	AC3
Number of Residues	19
Details	BINDING SITE FOR RESIDUE 1N7 A 403

Chain	Residue
A	GLN98
A	PHE99
A	GLY100
A	PRO276
A	GLY277
A	GLU280
A	ARG284
A	MET324
A	LEU330
A	1N7406
A	1N7407
A	HOH508
A	HOH544
A	HOH594
A	HOH605
A	HOH718
A	HOH774
A	HOH830
A	HOH869

---

site_id	AC4
Number of Residues	13
Details	BINDING SITE FOR RESIDUE 1N7 A 404

Chain	Residue
A	LYS37
A	ASP40
A	LYS170
A	ARG284
A	SER297
A	LYS315
A	ASP316
A	THR317
A	HOH598
A	HOH642
A	HOH669
A	HOH687
A	HOH693

---

site_id	AC5
Number of Residues	10
Details	BINDING SITE FOR RESIDUE 1N7 A 405

Chain	Residue
A	ARG29
A	GLU33
A	THR247
A	LEU250
A	1N7406
A	HOH593
A	HOH597
A	HOH603
A	HOH793
A	HOH833

---

site_id	AC6
Number of Residues	7
Details	BINDING SITE FOR RESIDUE 1N7 A 406

Chain	Residue
A	THR317
A	ALA318
A	1N7403
A	1N7405
A	HOH628
A	HOH831
A	HOH842

---

site_id	AC7
Number of Residues	9
Details	BINDING SITE FOR RESIDUE 1N7 A 407

Chain	Residue
A	LYS128
A	MET324
A	GLU328
A	1N7403
A	HOH701
A	HOH734
A	HOH763
A	HOH764
A	HOH791

---

site_id	AC8
Number of Residues	2
Details	BINDING SITE FOR RESIDUE H2S A 408

Chain	Residue
A	CYS311
A	CYS319

---

site_id	AC9
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CL A 409

Chain	Residue
A	THR268
A	ALA270
A	TYR306
A	HOH808
A	HOH823

---

site_id	BC1
Number of Residues	3
Details	BINDING SITE FOR RESIDUE CL A 410

Chain	Residue
A	ARG54
A	THR134
A	ARG155

---

site_id	BC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CL A 411

Chain	Residue
A	ARG159
A	PRO266
A	HOH638
A	HOH822

---

site_id	BC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CO3 A 412

Chain	Residue
A	PHE246
A	HOH552
A	HOH583
A	HOH773

---

Functional Information from PROSITE/UniProt

site_id	PS00216
Number of Residues	18
Details	SUGAR_TRANSPORT_1 Sugar transport proteins signature 1. VMKMIELLGRKpgrdwgG

Chain	Residue	Details
A	VAL323-GLY340

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	BINDING: BINDING => ECO:0000255|PIRSR:PIRSR004762-1, ECO:0000269|PubMed:16137685, ECO:0000269|PubMed:18400755, ECO:0000269|PubMed:19706452, ECO:0007744|PDB:3CIW, ECO:0007744|PDB:3CIX, ECO:0007744|PDB:3IIX

Chain	Residue	Details
A	CYS63

---

site_id	SWS_FT_FI2
Number of Residues	2
Details	BINDING: BINDING => ECO:0000255|PIRSR:PIRSR004762-1, ECO:0000269|PubMed:16137685, ECO:0007744|PDB:3CIW, ECO:0007744|PDB:3CIX, ECO:0007744|PDB:3IIX

Chain	Residue	Details
A	CYS67
A	CYS70

---

site_id	SWS_FT_FI3
Number of Residues	1
Details	BINDING: BINDING => ECO:0007744|PDB:3CIX, ECO:0007744|PDB:3IIZ, ECO:0007744|PDB:4JXC, ECO:0007744|PDB:4JY8, ECO:0007744|PDB:4JY9, ECO:0007744|PDB:4JYE

Chain	Residue	Details
A	CYS311

---

site_id	SWS_FT_FI4
Number of Residues	2
Details	BINDING: BINDING => ECO:0007744|PDB:3CIX, ECO:0007744|PDB:4JY8, ECO:0007744|PDB:4JY9, ECO:0007744|PDB:4JYE

Chain	Residue	Details
A	CYS319
A	CSO322

---