4JYE

X-ray snapshots of possible intermediates in the time course of synthesis and degradation of protein-bound Fe4S4 clusters.

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003824	molecular_function	catalytic activity
A	0016491	molecular_function	oxidoreductase activity
A	0016740	molecular_function	transferase activity
A	0042364	biological_process	water-soluble vitamin biosynthetic process
A	0044272	biological_process	sulfur compound biosynthetic process
A	0046872	molecular_function	metal ion binding
A	0051536	molecular_function	iron-sulfur cluster binding
A	0051537	molecular_function	2 iron, 2 sulfur cluster binding
A	0051539	molecular_function	4 iron, 4 sulfur cluster binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SF4 A 401

Chain	Residue
A	CYS63
A	CYS67
A	CYS70
A	SAH402

---

site_id	AC2
Number of Residues	18
Details	BINDING SITE FOR RESIDUE SAH A 402

Chain	Residue
A	ARG180
A	MET199
A	PRO229
A	ILE231
A	TYR303
A	LEU305
A	SF4401
A	HOH512
A	HOH518
A	HOH520
A	HOH529
A	HOH567
A	HOH801
A	TYR69
A	SER108
A	SER136
A	ARG159
A	GLU161

---

site_id	AC3
Number of Residues	20
Details	BINDING SITE FOR RESIDUE 1N7 A 403

Chain	Residue
A	VAL97
A	GLN98
A	PHE99
A	GLY100
A	PRO276
A	GLY277
A	GLU280
A	ARG284
A	MET324
A	LEU330
A	1N7406
A	1N7407
A	HOH509
A	HOH545
A	HOH593
A	HOH603
A	HOH709
A	HOH766
A	HOH785
A	HOH823

---

site_id	AC4
Number of Residues	15
Details	BINDING SITE FOR RESIDUE 1N7 A 404

Chain	Residue
A	LYS37
A	ASP40
A	LYS170
A	ARG284
A	SER297
A	LYS315
A	ASP316
A	THR317
A	1N7406
A	HOH597
A	HOH639
A	HOH663
A	HOH682
A	HOH688
A	HOH761

---

site_id	AC5
Number of Residues	10
Details	BINDING SITE FOR RESIDUE 1N7 A 405

Chain	Residue
A	ARG29
A	GLU33
A	THR247
A	LEU250
A	1N7406
A	HOH592
A	HOH596
A	HOH601
A	HOH787
A	HOH827

---

site_id	AC6
Number of Residues	7
Details	BINDING SITE FOR RESIDUE 1N7 A 406

Chain	Residue
A	THR317
A	ALA318
A	1N7403
A	1N7404
A	1N7405
A	HOH712
A	HOH824

---

site_id	AC7
Number of Residues	14
Details	BINDING SITE FOR RESIDUE 1N7 A 407

Chain	Residue
A	LYS128
A	PRO321
A	MET324
A	LYS325
A	GLU328
A	1N7403
A	HOH724
A	HOH772
A	HOH777
A	HOH785
A	HOH803
A	HOH837
A	HOH847
A	HOH849

---

site_id	AC8
Number of Residues	5
Details	BINDING SITE FOR RESIDUE F3S A 408

Chain	Residue
A	ARG279
A	CYS311
A	CYS319
A	CYS322
A	HOH501

---

site_id	AC9
Number of Residues	3
Details	BINDING SITE FOR RESIDUE BR A 409

Chain	Residue
A	ARG54
A	THR134
A	ARG155

---

site_id	BC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE BR A 410

Chain	Residue
A	HOH817
A	HOH818
A	ARG159
A	ALA270
A	TYR306

---

site_id	BC2
Number of Residues	3
Details	BINDING SITE FOR RESIDUE BR A 411

Chain	Residue
A	ARG159
A	PRO266
A	HOH635

---

site_id	BC3
Number of Residues	3
Details	BINDING SITE FOR RESIDUE BR A 412

Chain	Residue
A	ARG64
A	HOH566
A	HOH583

---

site_id	BC4
Number of Residues	1
Details	BINDING SITE FOR RESIDUE BR A 413

Chain	Residue
A	HOH872

---

site_id	BC5
Number of Residues	3
Details	BINDING SITE FOR RESIDUE CO3 A 414

Chain	Residue
A	PHE246
A	HOH582
A	HOH765

---

Functional Information from PROSITE/UniProt

site_id	PS00216
Number of Residues	18
Details	SUGAR_TRANSPORT_1 Sugar transport proteins signature 1. VMKMIELLGRKpgrdwgG

Chain	Residue	Details
A	VAL323-GLY340

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"PIRSR","id":"PIRSR004762-1","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"16137685","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"18400755","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19706452","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3CIW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3CIX","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3IIX","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"PIRSR","id":"PIRSR004762-1","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"16137685","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3CIW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3CIX","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3IIX","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"PDB","id":"3CIX","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3IIZ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4JXC","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4JY8","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4JY9","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4JYE","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"PDB","id":"3CIX","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4JY8","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4JY9","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4JYE","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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