4JYD

X-ray snapshots of possible intermediates in the time course of synthesis and degradation of protein-bound Fe4S4 clusters.

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003824	molecular_function	catalytic activity
A	0016491	molecular_function	oxidoreductase activity
A	0016740	molecular_function	transferase activity
A	0042364	biological_process	water-soluble vitamin biosynthetic process
A	0044272	biological_process	sulfur compound biosynthetic process
A	0046872	molecular_function	metal ion binding
A	0051536	molecular_function	iron-sulfur cluster binding
A	0051537	molecular_function	2 iron, 2 sulfur cluster binding
A	0051539	molecular_function	4 iron, 4 sulfur cluster binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	7
Details	BINDING SITE FOR RESIDUE SF4 A 401

Chain	Residue
A	CYS63
A	LYS65
A	CYS67
A	TYR69
A	CYS70
A	GLY109
A	SAH402

---

site_id	AC2
Number of Residues	19
Details	BINDING SITE FOR RESIDUE SAH A 402

Chain	Residue
A	SER108
A	SER136
A	ARG159
A	GLU161
A	ARG180
A	MET199
A	PRO229
A	ILE231
A	TYR303
A	LEU305
A	TYR306
A	SF4401
A	HOH512
A	HOH518
A	HOH520
A	HOH529
A	HOH803
A	TYR69
A	GLN107

---

site_id	AC3
Number of Residues	19
Details	BINDING SITE FOR RESIDUE CPS A 403

Chain	Residue
A	VAL97
A	GLN98
A	PHE99
A	GLY100
A	PRO276
A	GLY277
A	GLU280
A	ARG284
A	MET324
A	LEU330
A	1N7405
A	1N7406
A	1N7407
A	HOH509
A	HOH545
A	HOH595
A	HOH605
A	HOH711
A	HOH765

---

site_id	AC4
Number of Residues	15
Details	BINDING SITE FOR RESIDUE 1N7 A 404

Chain	Residue
A	LYS37
A	ASP40
A	LYS170
A	ARG284
A	SER297
A	LYS315
A	ASP316
A	THR317
A	1N7406
A	HOH599
A	HOH642
A	HOH669
A	HOH683
A	HOH688
A	HOH792

---

site_id	AC5
Number of Residues	13
Details	BINDING SITE FOR RESIDUE 1N7 A 405

Chain	Residue
A	ARG29
A	GLU33
A	PHE246
A	THR247
A	LEU250
A	CPS403
A	1N7406
A	HOH594
A	HOH598
A	HOH603
A	HOH787
A	HOH824
A	HOH843

---

site_id	AC6
Number of Residues	8
Details	BINDING SITE FOR RESIDUE 1N7 A 406

Chain	Residue
A	THR317
A	ALA318
A	CPS403
A	1N7404
A	1N7405
A	HOH627
A	HOH714
A	HOH833

---

site_id	AC7
Number of Residues	10
Details	BINDING SITE FOR RESIDUE 1N7 A 407

Chain	Residue
A	LYS128
A	MET324
A	LYS325
A	GLU328
A	CPS403
A	HOH695
A	HOH725
A	HOH755
A	HOH756
A	HOH785

---

site_id	AC8
Number of Residues	4
Details	BINDING SITE FOR RESIDUE FE A 408

Chain	Residue
A	CYS311
A	CYS319
A	H2S409
A	H2S410

---

site_id	AC9
Number of Residues	4
Details	BINDING SITE FOR RESIDUE H2S A 409

Chain	Residue
A	ARG279
A	CYS311
A	VAL323
A	FE408

---

site_id	BC1
Number of Residues	3
Details	BINDING SITE FOR RESIDUE H2S A 410

Chain	Residue
A	GLU314
A	CYS319
A	FE408

---

site_id	BC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE BR A 411

Chain	Residue
A	ARG64
A	TRP140
A	PRO141
A	HOH567
A	HOH585

---

site_id	BC3
Number of Residues	3
Details	BINDING SITE FOR RESIDUE BR A 412

Chain	Residue
A	ARG54
A	THR134
A	ARG155

---

site_id	BC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE BR A 413

Chain	Residue
A	ARG159
A	PRO266
A	HOH638
A	HOH816

---

site_id	BC5
Number of Residues	4
Details	BINDING SITE FOR RESIDUE BR A 414

Chain	Residue
A	ARG159
A	ALA270
A	TYR306
A	HOH803

---

Functional Information from PROSITE/UniProt

site_id	PS00216
Number of Residues	18
Details	SUGAR_TRANSPORT_1 Sugar transport proteins signature 1. VMKMIELLGRKpgrdwgG

Chain	Residue	Details
A	VAL323-GLY340

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"PIRSR","id":"PIRSR004762-1","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"16137685","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"18400755","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19706452","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3CIW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3CIX","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3IIX","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"PIRSR","id":"PIRSR004762-1","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"16137685","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3CIW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3CIX","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3IIX","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"PDB","id":"3CIX","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3IIZ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4JXC","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4JY8","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4JY9","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4JYE","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"PDB","id":"3CIX","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4JY8","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4JY9","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4JYE","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---