4JY9

X-ray snapshots of possible intermediates in the time course of synthesis and degradation of protein-bound Fe4S4 clusters

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003824	molecular_function	catalytic activity
A	0016491	molecular_function	oxidoreductase activity
A	0016740	molecular_function	transferase activity
A	0042364	biological_process	water-soluble vitamin biosynthetic process
A	0044272	biological_process	sulfur compound biosynthetic process
A	0046872	molecular_function	metal ion binding
A	0051536	molecular_function	iron-sulfur cluster binding
A	0051537	molecular_function	2 iron, 2 sulfur cluster binding
A	0051539	molecular_function	4 iron, 4 sulfur cluster binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SF4 A 401

Chain	Residue
A	CYS63
A	CYS67
A	CYS70
A	SAH402

---

site_id	AC2
Number of Residues	18
Details	BINDING SITE FOR RESIDUE SAH A 402

Chain	Residue
A	ARG180
A	MET199
A	PRO229
A	ILE231
A	TYR303
A	LEU305
A	SF4401
A	HOH512
A	HOH518
A	HOH520
A	HOH567
A	HOH652
A	HOH829
A	TYR69
A	SER108
A	SER136
A	ARG159
A	GLU161

---

site_id	AC3
Number of Residues	15
Details	BINDING SITE FOR RESIDUE 1N7 A 403

Chain	Residue
A	GLN98
A	PHE99
A	GLY100
A	GLU280
A	ARG284
A	MET324
A	LEU330
A	1N7406
A	1N7407
A	1N7410
A	HOH509
A	HOH544
A	HOH594
A	HOH606
A	HOH828

---

site_id	AC4
Number of Residues	13
Details	BINDING SITE FOR RESIDUE 1N7 A 404

Chain	Residue
A	LYS37
A	ASP40
A	LYS170
A	ARG284
A	SER297
A	LYS315
A	ASP316
A	THR317
A	HOH598
A	HOH647
A	HOH675
A	HOH693
A	HOH699

---

site_id	AC5
Number of Residues	8
Details	BINDING SITE FOR RESIDUE 1N7 A 405

Chain	Residue
A	ARG29
A	GLU33
A	THR247
A	1N7406
A	HOH593
A	HOH597
A	HOH603
A	HOH797

---

site_id	AC6
Number of Residues	10
Details	BINDING SITE FOR RESIDUE 1N7 A 406

Chain	Residue
A	ARG29
A	LYS315
A	THR317
A	ALA318
A	1N7403
A	1N7405
A	HOH725
A	HOH728
A	HOH790
A	HOH826

---

site_id	AC7
Number of Residues	9
Details	BINDING SITE FOR RESIDUE 1N7 A 407

Chain	Residue
A	LYS128
A	MET324
A	LYS325
A	GLU328
A	1N7403
A	HOH707
A	HOH742
A	HOH779
A	HOH780

---

site_id	AC8
Number of Residues	5
Details	BINDING SITE FOR RESIDUE 1N7 A 408

Chain	Residue
A	ASP337
A	TRP338
A	GLY339
A	GLY340
A	LYS342

---

site_id	AC9
Number of Residues	5
Details	BINDING SITE FOR RESIDUE FES A 409

Chain	Residue
A	ARG279
A	CYS311
A	CYS319
A	CYS322
A	HOH501

---

site_id	BC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE 1N7 A 410

Chain	Residue
A	GLY100
A	LYS102
A	LYS325
A	1N7403
A	HOH570
A	HOH776

---

site_id	BC2
Number of Residues	3
Details	BINDING SITE FOR RESIDUE CL A 411

Chain	Residue
A	ARG54
A	THR134
A	ARG155

---

site_id	BC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CL A 412

Chain	Residue
A	HOH845
A	ARG159
A	MET291
A	HOH643

---

site_id	BC4
Number of Residues	8
Details	BINDING SITE FOR RESIDUE CL A 413

Chain	Residue
A	ARG159
A	THR268
A	THR269
A	ALA270
A	TYR306
A	HOH829
A	HOH842
A	HOH843

---

Functional Information from PROSITE/UniProt

site_id	PS00216
Number of Residues	18
Details	SUGAR_TRANSPORT_1 Sugar transport proteins signature 1. VMKMIELLGRKpgrdwgG

Chain	Residue	Details
A	VAL323-GLY340

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	219
Details	Domain: {"description":"Radical SAM core","evidences":[{"source":"PROSITE-ProRule","id":"PRU01266","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"PIRSR","id":"PIRSR004762-1","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"16137685","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"18400755","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19706452","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3CIW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3CIX","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3IIX","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"PIRSR","id":"PIRSR004762-1","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"16137685","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3CIW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3CIX","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3IIX","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"PDB","id":"3CIX","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3IIZ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4JXC","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4JY8","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4JY9","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4JYE","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"PDB","id":"3CIX","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4JY8","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4JY9","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4JYE","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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