4JY1

CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE IN COMPLEX WITH COMPOUND 5

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003723	molecular_function	RNA binding
A	0003968	molecular_function	RNA-dependent RNA polymerase activity
A	0039694	biological_process	viral RNA genome replication
B	0003723	molecular_function	RNA binding
B	0003968	molecular_function	RNA-dependent RNA polymerase activity
B	0039694	biological_process	viral RNA genome replication

Functional Information from PDB Data

site_id	AC1
Number of Residues	8
Details	BINDING SITE FOR RESIDUE NN3 A 601

Chain	Residue
A	LEU419
A	ARG422
A	MET423
A	HIS475
A	SER476
A	TYR477
A	ILE482
A	TRP528

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	6
Details	BINDING: BINDING => ECO:0000250|UniProtKB:P26663

Chain	Residue	Details
A	ASP220
A	ASP318
A	ASP319
B	ASP220
B	ASP318
B	ASP319

---

site_id	SWS_FT_FI2
Number of Residues	4
Details	MOD_RES: Phosphoserine; by host => ECO:0000250|UniProtKB:P26662

Chain	Residue	Details
A	SER29
A	SER42
B	SER29
B	SER42

---