4JXC
X-ray snapshots of possible intermediates in the time course of synthesis and degradation of protein-bound Fe4S4 clusters
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0016740 | molecular_function | transferase activity |
| A | 0018130 | biological_process | obsolete heterocycle biosynthetic process |
| A | 0042364 | biological_process | water-soluble vitamin biosynthetic process |
| A | 0044271 | biological_process | obsolete cellular nitrogen compound biosynthetic process |
| A | 0044272 | biological_process | sulfur compound biosynthetic process |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0051536 | molecular_function | iron-sulfur cluster binding |
| A | 0051537 | molecular_function | 2 iron, 2 sulfur cluster binding |
| A | 0051539 | molecular_function | 4 iron, 4 sulfur cluster binding |
| A | 1901362 | biological_process | organic cyclic compound biosynthetic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SF4 A 401 |
| Chain | Residue |
| A | CYS63 |
| A | CYS67 |
| A | CYS70 |
| A | GLY109 |
| A | SAM402 |
| site_id | AC2 |
| Number of Residues | 19 |
| Details | BINDING SITE FOR RESIDUE SAM A 402 |
| Chain | Residue |
| A | ARG159 |
| A | GLU161 |
| A | ARG180 |
| A | MET199 |
| A | PRO229 |
| A | ILE231 |
| A | TYR303 |
| A | LEU305 |
| A | TYR306 |
| A | SF4401 |
| A | HOH511 |
| A | HOH517 |
| A | HOH519 |
| A | HOH528 |
| A | HOH567 |
| A | TYR69 |
| A | SER108 |
| A | SER136 |
| A | GLY138 |
| site_id | AC3 |
| Number of Residues | 16 |
| Details | BINDING SITE FOR RESIDUE 1N7 A 403 |
| Chain | Residue |
| A | GLN98 |
| A | PHE99 |
| A | GLY100 |
| A | GLU280 |
| A | ARG284 |
| A | MET324 |
| A | LEU330 |
| A | 1N7406 |
| A | 1N7407 |
| A | IPA412 |
| A | HOH508 |
| A | HOH544 |
| A | HOH594 |
| A | HOH606 |
| A | HOH812 |
| A | HOH813 |
| site_id | AC4 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE 1N7 A 404 |
| Chain | Residue |
| A | LYS37 |
| A | ASP40 |
| A | LYS170 |
| A | ARG284 |
| A | SER297 |
| A | LYS315 |
| A | ASP316 |
| A | THR317 |
| A | HOH598 |
| A | HOH648 |
| A | HOH676 |
| A | HOH695 |
| A | HOH701 |
| A | HOH821 |
| site_id | AC5 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE 1N7 A 405 |
| Chain | Residue |
| A | ARG29 |
| A | GLU33 |
| A | THR247 |
| A | LEU250 |
| A | 1N7406 |
| A | HOH593 |
| A | HOH597 |
| A | HOH603 |
| A | HOH798 |
| site_id | AC6 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE 1N7 A 406 |
| Chain | Residue |
| A | ARG29 |
| A | LYS315 |
| A | THR317 |
| A | ALA318 |
| A | 1N7403 |
| A | 1N7405 |
| A | 1N7407 |
| A | HOH632 |
| A | HOH728 |
| A | HOH828 |
| site_id | AC7 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE 1N7 A 407 |
| Chain | Residue |
| A | LYS128 |
| A | PRO321 |
| A | MET324 |
| A | LYS325 |
| A | GLU328 |
| A | 1N7403 |
| A | 1N7406 |
| A | HOH530 |
| A | HOH744 |
| A | HOH799 |
| A | HOH805 |
| site_id | AC8 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE GOL A 408 |
| Chain | Residue |
| A | VAL47 |
| A | HIS52 |
| A | ASP262 |
| A | ASN264 |
| A | GLY340 |
| A | ARG341 |
| A | LYS342 |
| A | HOH550 |
| site_id | AC9 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE FES A 409 |
| Chain | Residue |
| A | HOH622 |
| A | ARG279 |
| A | CYS311 |
| A | CYS319 |
| A | CYS322 |
| A | VAL323 |
| A | H2S410 |
| A | H2S411 |
| site_id | BC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE H2S A 410 |
| Chain | Residue |
| A | CYS311 |
| A | CYS319 |
| A | FES409 |
| site_id | BC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE H2S A 411 |
| Chain | Residue |
| A | ARG279 |
| A | CYS322 |
| A | MET326 |
| A | FES409 |
| site_id | BC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE IPA A 412 |
| Chain | Residue |
| A | LYS102 |
| A | LYS325 |
| A | 1N7403 |
| A | HOH570 |
| A | HOH779 |
| site_id | BC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL A 413 |
| Chain | Residue |
| A | ARG54 |
| A | THR134 |
| A | ARG155 |
| A | MET224 |
| site_id | BC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CL A 414 |
| Chain | Residue |
| A | ARG159 |
| A | THR269 |
| A | ALA270 |
| A | TYR306 |
| A | HOH822 |
| site_id | BC6 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE SO4 A 415 |
| Chain | Residue |
| A | ASP337 |
| A | TRP338 |
| A | GLY339 |
| A | GLY340 |
| A | LYS342 |
| A | HOH536 |
| A | HOH720 |
Functional Information from PROSITE/UniProt
| site_id | PS00216 |
| Number of Residues | 18 |
| Details | SUGAR_TRANSPORT_1 Sugar transport proteins signature 1. VMKMIELLGRKpgrdwgG |
| Chain | Residue | Details |
| A | VAL323-GLY340 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | BINDING: BINDING => ECO:0000255|PIRSR:PIRSR004762-1, ECO:0000269|PubMed:16137685, ECO:0000269|PubMed:18400755, ECO:0000269|PubMed:19706452, ECO:0007744|PDB:3CIW, ECO:0007744|PDB:3CIX, ECO:0007744|PDB:3IIX |
| Chain | Residue | Details |
| A | CYS63 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | BINDING: BINDING => ECO:0000255|PIRSR:PIRSR004762-1, ECO:0000269|PubMed:16137685, ECO:0007744|PDB:3CIW, ECO:0007744|PDB:3CIX, ECO:0007744|PDB:3IIX |
| Chain | Residue | Details |
| A | CYS67 | |
| A | CYS70 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | BINDING: BINDING => ECO:0007744|PDB:3CIX, ECO:0007744|PDB:3IIZ, ECO:0007744|PDB:4JXC, ECO:0007744|PDB:4JY8, ECO:0007744|PDB:4JY9, ECO:0007744|PDB:4JYE |
| Chain | Residue | Details |
| A | CYS311 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | BINDING: BINDING => ECO:0007744|PDB:3CIX, ECO:0007744|PDB:4JY8, ECO:0007744|PDB:4JY9, ECO:0007744|PDB:4JYE |
| Chain | Residue | Details |
| A | CYS319 | |
| A | CYS322 |
