4JTF

Crystal structure of F114R mutant of 3-deoxy-D-manno-octulosonate 8-phosphate synthase (KDO8PS) from Neisseria meningitidis

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0008676	molecular_function	3-deoxy-8-phosphooctulonate synthase activity
A	0009058	biological_process	biosynthetic process
A	0009103	biological_process	lipopolysaccharide biosynthetic process
A	0016740	molecular_function	transferase activity
A	0019294	biological_process	keto-3-deoxy-D-manno-octulosonic acid biosynthetic process
B	0005737	cellular_component	cytoplasm
B	0005829	cellular_component	cytosol
B	0008676	molecular_function	3-deoxy-8-phosphooctulonate synthase activity
B	0009058	biological_process	biosynthetic process
B	0009103	biological_process	lipopolysaccharide biosynthetic process
B	0016740	molecular_function	transferase activity
B	0019294	biological_process	keto-3-deoxy-D-manno-octulosonic acid biosynthetic process
C	0005737	cellular_component	cytoplasm
C	0005829	cellular_component	cytosol
C	0008676	molecular_function	3-deoxy-8-phosphooctulonate synthase activity
C	0009058	biological_process	biosynthetic process
C	0009103	biological_process	lipopolysaccharide biosynthetic process
C	0016740	molecular_function	transferase activity
C	0019294	biological_process	keto-3-deoxy-D-manno-octulosonic acid biosynthetic process
D	0005737	cellular_component	cytoplasm
D	0005829	cellular_component	cytosol
D	0008676	molecular_function	3-deoxy-8-phosphooctulonate synthase activity
D	0009058	biological_process	biosynthetic process
D	0009103	biological_process	lipopolysaccharide biosynthetic process
D	0016740	molecular_function	transferase activity
D	0019294	biological_process	keto-3-deoxy-D-manno-octulosonic acid biosynthetic process

Functional Information from PDB Data

site_id	AC1
Number of Residues	7
Details	BINDING SITE FOR RESIDUE GOL B 301

Chain	Residue
A	ASP177
A	LEU179
B	ASP172
B	LEU174
B	SER211
B	ARG214
B	HOH476

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site_id	AC2
Number of Residues	3
Details	BINDING SITE FOR RESIDUE CL B 302

Chain	Residue
B	HOH491
B	ILE63
B	LYS265

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site_id	AC3
Number of Residues	3
Details	BINDING SITE FOR RESIDUE CL B 303

Chain	Residue
B	ALA113
B	PRO137
B	GLN138

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site_id	AC4
Number of Residues	3
Details	BINDING SITE FOR RESIDUE CL C 301

Chain	Residue
C	ALA113
C	GLN138
C	ARG165

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site_id	AC5
Number of Residues	3
Details	BINDING SITE FOR RESIDUE CL C 302

Chain	Residue
C	GLN110
C	LYS135
C	HIS199

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site_id	AC6
Number of Residues	6
Details	BINDING SITE FOR RESIDUE NA C 303

Chain	Residue
B	HOH495
C	ALA103
C	CYS106
C	ASN130
C	HOH426
C	HOH434

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site_id	AC7
Number of Residues	8
Details	BINDING SITE FOR RESIDUE GOL D 301

Chain	Residue
C	ARG229
C	GLN274
C	ILE276
C	LEU277
C	HOH420
C	HOH451
D	LEU219
D	ARG263

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site_id	AC8
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CL D 302

Chain	Residue
D	LYS52
D	GLN110
D	LYS135
D	HIS199
D	PHE234

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site_id	AC9
Number of Residues	3
Details	BINDING SITE FOR RESIDUE CL D 303

Chain	Residue
D	ALA113
D	GLN138
D	ARG165

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