Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004517 | molecular_function | nitric-oxide synthase activity |
| A | 0006809 | biological_process | nitric oxide biosynthetic process |
| B | 0004517 | molecular_function | nitric-oxide synthase activity |
| B | 0006809 | biological_process | nitric oxide biosynthetic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 18 |
| Details | BINDING SITE FOR RESIDUE HEM A 801 |
| Chain | Residue |
| A | TRP409 |
| A | MET589 |
| A | GLU592 |
| A | TRP678 |
| A | TYR706 |
| A | H4B804 |
| A | QJ2805 |
| A | HOH936 |
| A | HOH1004 |
| A | HOH1077 |
| A | ARG414 |
| A | CYS415 |
| A | VAL416 |
| A | SER457 |
| A | PHE584 |
| A | SER585 |
| A | GLY586 |
| A | TRP587 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ACT A 802 |
| Chain | Residue |
| A | TRP587 |
| A | SER657 |
| A | HOH992 |
| A | HOH1036 |
| site_id | AC3 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE QJ2 A 803 |
| Chain | Residue |
| A | GLU323 |
| A | GLU573 |
| A | GLU578 |
| A | ARG699 |
| A | PHE704 |
| A | GLU705 |
| A | TYR706 |
| A | HOH964 |
| A | HOH1006 |
| site_id | AC4 |
| Number of Residues | 15 |
| Details | BINDING SITE FOR RESIDUE H4B A 804 |
| Chain | Residue |
| A | SER334 |
| A | MET336 |
| A | ARG596 |
| A | VAL677 |
| A | TRP678 |
| A | HEM801 |
| A | CL807 |
| A | HOH951 |
| A | HOH1004 |
| A | HOH1068 |
| B | TRP676 |
| B | PHE691 |
| B | HIS692 |
| B | GLN693 |
| B | GLU694 |
| site_id | AC5 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE QJ2 A 805 |
| Chain | Residue |
| A | SER477 |
| A | GLN478 |
| A | ARG481 |
| A | VAL567 |
| A | ASN569 |
| A | MET570 |
| A | PHE584 |
| A | GLY586 |
| A | TRP587 |
| A | GLU592 |
| A | HEM801 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ZN A 806 |
| Chain | Residue |
| A | ARG596 |
| A | ASP600 |
| A | CL807 |
| A | CL808 |
| B | HIS692 |
| site_id | AC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CL A 807 |
| Chain | Residue |
| A | ARG596 |
| A | ASP600 |
| A | H4B804 |
| A | ZN806 |
| A | CL808 |
| site_id | AC8 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CL A 808 |
| Chain | Residue |
| A | ARG596 |
| A | ASP600 |
| A | ZN806 |
| A | CL807 |
| B | SER686 |
| B | HIS692 |
| site_id | AC9 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN A 809 |
| Chain | Residue |
| A | CYS326 |
| A | CYS331 |
| B | CYS326 |
| B | CYS331 |
| site_id | BC1 |
| Number of Residues | 17 |
| Details | BINDING SITE FOR RESIDUE HEM B 801 |
| Chain | Residue |
| B | TRP409 |
| B | ARG414 |
| B | CYS415 |
| B | SER457 |
| B | PHE584 |
| B | SER585 |
| B | TRP587 |
| B | GLU592 |
| B | TRP678 |
| B | PHE704 |
| B | TYR706 |
| B | H4B802 |
| B | ACT804 |
| B | QJ2805 |
| B | HOH1098 |
| B | HOH1130 |
| B | HOH1134 |
| site_id | BC2 |
| Number of Residues | 15 |
| Details | BINDING SITE FOR RESIDUE H4B B 802 |
| Chain | Residue |
| B | SER334 |
| B | MET336 |
| B | ARG596 |
| B | VAL677 |
| B | TRP678 |
| B | HEM801 |
| B | CL807 |
| B | HOH1016 |
| B | HOH1077 |
| B | HOH1098 |
| A | TRP676 |
| A | PHE691 |
| A | HIS692 |
| A | GLN693 |
| A | GLU694 |
| site_id | BC3 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE QJ2 B 803 |
| Chain | Residue |
| B | GLU323 |
| B | GLU573 |
| B | GLU578 |
| B | ARG699 |
| B | PHE704 |
| B | GLU705 |
| B | TYR706 |
| B | HOH1078 |
| site_id | BC4 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE ACT B 804 |
| Chain | Residue |
| B | TRP587 |
| B | VAL649 |
| B | HEM801 |
| B | HOH968 |
| B | HOH971 |
| B | HOH994 |
| B | HOH1081 |
| site_id | BC5 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE QJ2 B 805 |
| Chain | Residue |
| B | SER477 |
| B | GLN478 |
| B | ARG481 |
| B | VAL567 |
| B | ASN569 |
| B | MET570 |
| B | PHE584 |
| B | GLY586 |
| B | TRP587 |
| B | TYR588 |
| B | GLU592 |
| B | HEM801 |
| site_id | BC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ZN B 806 |
| Chain | Residue |
| A | HIS692 |
| B | ARG596 |
| B | ASP600 |
| B | CL807 |
| B | CL808 |
| site_id | BC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CL B 807 |
| Chain | Residue |
| B | ARG596 |
| B | ASP600 |
| B | H4B802 |
| B | ZN806 |
| B | CL808 |
| site_id | BC8 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CL B 808 |
| Chain | Residue |
| A | SER686 |
| B | ARG596 |
| B | ASP600 |
| B | ZN806 |
| B | CL807 |
Functional Information from PROSITE/UniProt
| site_id | PS60001 |
| Number of Residues | 8 |
| Details | NOS Nitric oxide synthase (NOS) signature. RCVGRIqW |
| Chain | Residue | Details |
| A | ARG414-TRP421 | |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| A | SER334 | |
| B | SER334 | |
| B | GLN478 | |
| B | TRP587 | |
| B | TYR588 | |
| B | GLU592 | |
| B | VAL677 | |
| B | TRP678 | |
| B | PHE691 | |
| B | TYR706 | |
| A | GLN478 | |
| A | TRP587 | |
| A | TYR588 | |
| A | GLU592 | |
| A | VAL677 | |
| A | TRP678 | |
| A | PHE691 | |
| A | TYR706 | |
| Chain | Residue | Details |
| A | CYS415 | |
| B | CYS415 | |
