4JR9
Crystal structure of nitrate/nitrite exchanger NarK
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005452 | molecular_function | solute:inorganic anion antiporter activity |
| A | 0005886 | cellular_component | plasma membrane |
| A | 0015103 | molecular_function | inorganic anion transmembrane transporter activity |
| A | 0015112 | molecular_function | nitrate transmembrane transporter activity |
| A | 0015113 | molecular_function | nitrite transmembrane transporter activity |
| A | 0015291 | molecular_function | secondary active transmembrane transporter activity |
| A | 0015706 | biological_process | nitrate transmembrane transport |
| A | 0015707 | biological_process | nitrite transport |
| A | 0016020 | cellular_component | membrane |
| A | 0022857 | molecular_function | transmembrane transporter activity |
| A | 0042128 | biological_process | nitrate assimilation |
| A | 0043602 | biological_process | nitrate catabolic process |
| A | 0055085 | biological_process | transmembrane transport |
Functional Information from PROSITE/UniProt
| site_id | PS00290 |
| Number of Residues | 7 |
| Details | IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YTCEATH |
| Chain | Residue | Details |
| L | TYR191-HIS197 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 109 |
| Details | TOPO_DOM: Cytoplasmic => ECO:0000269|PubMed:25959928, ECO:0007744|PDB:4U4T, ECO:0007744|PDB:4U4V |
| Chain | Residue | Details |
| A | MET1-ASN37 | |
| A | VAL96-ARG102 | |
| A | ALA152-ALA166 | |
| A | MET234-ARG253 | |
| A | ASP313-GLY316 | |
| A | SER374-ALA405 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 262 |
| Details | TRANSMEM: Helical => ECO:0000269|PubMed:25959928, ECO:0007744|PDB:4U4T, ECO:0007744|PDB:4U4V |
| Chain | Residue | Details |
| A | LEU38-ALA59 | |
| A | PHE348-ILE373 | |
| A | ALA406-SER427 | |
| A | VAL436-GLY458 | |
| A | LEU74-MET95 | |
| A | ARG103-ALA122 | |
| A | SER131-MET151 | |
| A | LEU167-VAL189 | |
| A | LEU212-GLY233 | |
| A | GLY254-SER281 | |
| A | ILE290-SER312 | |
| A | GLY317-THR338 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 63 |
| Details | TOPO_DOM: Periplasmic => ECO:0000269|PubMed:25959928, ECO:0007744|PDB:4U4T, ECO:0007744|PDB:4U4V |
| Chain | Residue | Details |
| A | VAL60-GLN73 | |
| A | VAL123-TYR130 | |
| A | SER190-TYR211 | |
| A | LYS282-GLN289 | |
| A | LEU339-SER347 | |
| A | SER428-PRO435 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 4 |
| Details | TOPO_DOM: Cytoplasmic => ECO:0000269|PubMed:15919996, ECO:0000269|PubMed:25959928, ECO:0007744|PDB:4U4T, ECO:0007744|PDB:4U4V |
| Chain | Residue | Details |
| A | ARG459-LYS463 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 2 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:23665960, ECO:0007744|PDB:4JRE |
| Chain | Residue | Details |
| A | ARG89 | |
| A | TYR263 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 1 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:25959928, ECO:0007744|PDB:4U4T, ECO:0007744|PDB:4U4W |
| Chain | Residue | Details |
| A | ASN175 |
| site_id | SWS_FT_FI7 |
| Number of Residues | 1 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:25959928, ECO:0007744|PDB:4U4T |
| Chain | Residue | Details |
| A | SER411 |
| site_id | SWS_FT_FI8 |
| Number of Residues | 1 |
| Details | SITE: Important for activity => ECO:0000305|PubMed:23665960, ECO:0000305|PubMed:25959928 |
| Chain | Residue | Details |
| A | ARG305 |
