Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004791 | molecular_function | thioredoxin-disulfide reductase (NADPH) activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0019430 | biological_process | removal of superoxide radicals |
| A | 0045454 | biological_process | cell redox homeostasis |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 37 |
| Details | BINDING SITE FOR RESIDUE FDA A 401 |
| Chain | Residue |
| A | ILE11 |
| A | GLY36 |
| A | LEU37 |
| A | GLN38 |
| A | GLY41 |
| A | GLN42 |
| A | LEU43 |
| A | ASN51 |
| A | ILE84 |
| A | ALA112 |
| A | THR113 |
| A | GLY12 |
| A | GLY114 |
| A | CYS139 |
| A | LEU254 |
| A | GLY285 |
| A | ASP286 |
| A | ARG293 |
| A | GLN294 |
| A | ALA295 |
| A | ALA298 |
| A | HOH501 |
| A | SER13 |
| A | HOH505 |
| A | HOH509 |
| A | HOH526 |
| A | HOH568 |
| A | HOH616 |
| A | HOH631 |
| A | HOH665 |
| A | HOH682 |
| A | GLY14 |
| A | PRO15 |
| A | ALA16 |
| A | TYR23 |
| A | ILE34 |
| A | ALA35 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE NA A 402 |
| Chain | Residue |
| A | THR269 |
| A | ALA270 |
| A | SER273 |
| A | HOH699 |
| A | HOH731 |
Functional Information from PROSITE/UniProt
| site_id | PS00573 |
| Number of Residues | 21 |
| Details | PYRIDINE_REDOX_2 Pyridine nucleotide-disulphide oxidoreductases class-II active site. CatCDGff..YrgkdVvVVGGGN |
| Chain | Residue | Details |
| A | CYS136-ASN156 | |
