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4JN0

Crystal structure of Cytochrome C Peroxidase W191G-Gateless in complex with 1H-pyrrolo[3,2-b]pyridine-6-carbaldehyde

Functional Information from GO Data
ChainGOidnamespacecontents
A0004601molecular_functionperoxidase activity
A0006979biological_processresponse to oxidative stress
A0020037molecular_functionheme binding
A0034599biological_processcellular response to oxidative stress
Functional Information from PDB Data
site_idAC1
Number of Residues25
DetailsBINDING SITE FOR RESIDUE HEM A 301
ChainResidue
APRO44
AHIS175
ALEU177
AGLY178
ALYS179
ATHR180
AHIS181
AASN184
ASER185
ALEU230
ATHR232
AARG48
A1MJ302
AHOH563
AHOH572
AHOH573
AHOH656
AHOH745
ATRP51
APRO145
AASP146
AALA147
ALEU171
AMET172
AALA174

site_idAC2
Number of Residues9
DetailsBINDING SITE FOR RESIDUE 1MJ A 302
ChainResidue
AHIS175
ALEU177
AGLY178
AGLY190
AGLY191
ATYR227
AMET228
AASP233
AHEM301

Functional Information from PROSITE/UniProt
site_idPS00435
Number of Residues11
DetailsPEROXIDASE_1 Peroxidases proximal heme-ligand signature. EVVALMGAHAL
ChainResidueDetails
AGLU167-LEU177

site_idPS00436
Number of Residues12
DetailsPEROXIDASE_2 Peroxidases active site signature. GPvlVRLaWHIS
ChainResidueDetails
AGLY43-SER54

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PDB entries from 2024-11-06

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