4JLU

Crystal structure of BRCA1 BRCT with doubly phosphorylated Abraxas

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003677	molecular_function	DNA binding
A	0004842	molecular_function	ubiquitin-protein transferase activity
A	0005634	cellular_component	nucleus
A	0006281	biological_process	DNA repair
A	0006974	biological_process	DNA damage response
A	0008270	molecular_function	zinc ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	11
Details	BINDING SITE FOR CHAIN B OF BRCA1-A COMPLEX SUBUNIT ABRAXAS

Chain	Residue
A	SER1655
A	LEU1701
A	LYS1702
A	GLY1656
A	THR1677
A	ASN1678
A	LEU1679
A	THR1691
A	GLU1698
A	ARG1699
A	THR1700

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	99
Details	Domain: {"description":"BRCT 2","evidences":[{"source":"PROSITE-ProRule","id":"PRU00033","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"26778126","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"17525340","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"17643121","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"17643122","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"26778126","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"18669648","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"19690332","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"20068231","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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