4JKL
Crystal Structure of Streptococcus agalactiae beta-glucuronidase in space group P21212
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004553 | molecular_function | hydrolase activity, hydrolyzing O-glycosyl compounds |
| A | 0004565 | molecular_function | beta-galactosidase activity |
| A | 0004566 | molecular_function | beta-glucuronidase activity |
| A | 0005102 | molecular_function | signaling receptor binding |
| A | 0005615 | cellular_component | extracellular space |
| A | 0005975 | biological_process | carbohydrate metabolic process |
| A | 0016798 | molecular_function | hydrolase activity, acting on glycosyl bonds |
| A | 0019391 | biological_process | glucuronoside catabolic process |
| A | 0030246 | molecular_function | carbohydrate binding |
| B | 0004553 | molecular_function | hydrolase activity, hydrolyzing O-glycosyl compounds |
| B | 0004565 | molecular_function | beta-galactosidase activity |
| B | 0004566 | molecular_function | beta-glucuronidase activity |
| B | 0005102 | molecular_function | signaling receptor binding |
| B | 0005615 | cellular_component | extracellular space |
| B | 0005975 | biological_process | carbohydrate metabolic process |
| B | 0016798 | molecular_function | hydrolase activity, acting on glycosyl bonds |
| B | 0019391 | biological_process | glucuronoside catabolic process |
| B | 0030246 | molecular_function | carbohydrate binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE MG A 601 |
| Chain | Residue |
| A | ASP535 |
| A | HIS592 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MG A 603 |
| Chain | Residue |
| A | ARG463 |
| A | TYR464 |
| A | TYR465 |
| A | HOH1051 |
| A | HOH1106 |
| site_id | AC3 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE MG B 601 |
| Chain | Residue |
| B | ARG463 |
| B | TYR465 |
Functional Information from PROSITE/UniProt
| site_id | PS00608 |
| Number of Residues | 15 |
| Details | GLYCOSYL_HYDROL_F2_2 Glycosyl hydrolases family 2 acid/base catalyst. DKNHPSVVMWVva.NE |
| Chain | Residue | Details |
| A | ASP394-GLU408 |
| site_id | PS00719 |
| Number of Residues | 26 |
| Details | GLYCOSYL_HYDROL_F2_1 Glycosyl hydrolases family 2 signature 1. NsFRTSHYPyseeMMrlaDrmGVLVI |
| Chain | Residue | Details |
| A | ASN323-ILE348 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | ACT_SITE: Proton donor => ECO:0000250|UniProtKB:P05804 |
| Chain | Residue | Details |
| A | GLU408 | |
| B | GLU408 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | ACT_SITE: Nucleophile => ECO:0000250|UniProtKB:P05804 |
| Chain | Residue | Details |
| A | GLU501 | |
| B | GLU501 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 14 |
| Details | BINDING: BINDING => ECO:0000250|UniProtKB:P05804 |
| Chain | Residue | Details |
| A | ASP160 | |
| B | ASN462 | |
| B | TYR468 | |
| B | GLU501 | |
| B | TRP546 | |
| B | LYS565 | |
| A | ASN407 | |
| A | ASN462 | |
| A | TYR468 | |
| A | GLU501 | |
| A | TRP546 | |
| A | LYS565 | |
| B | ASP160 | |
| B | ASN407 |
