4JKH

Open and closed forms of D1781E human PRP8 RNase H-like domain with bound Mg ion

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000398	biological_process	mRNA splicing, via spliceosome
A	0005681	cellular_component	spliceosomal complex
B	0000398	biological_process	mRNA splicing, via spliceosome
B	0005681	cellular_component	spliceosomal complex

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CL A 2001

Chain	Residue
A	GLN1890
A	ARG1941
A	HIS1944
A	HOH2324

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site_id	AC2
Number of Residues	1
Details	BINDING SITE FOR RESIDUE CL A 2002

Chain	Residue
A	GLY1867

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site_id	AC3
Number of Residues	7
Details	BINDING SITE FOR RESIDUE GOL A 2003

Chain	Residue
A	GLN1890
A	LEU1891
A	GLN1894
A	GLU1781
A	THR1864
A	ARG1865
A	LEU1889

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site_id	AC4
Number of Residues	7
Details	BINDING SITE FOR RESIDUE GOL A 2004

Chain	Residue
A	GLU1911
A	PRO1912
A	HOH2193
A	HOH2275
A	HOH2312
B	LYS1908
B	GLN1913

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site_id	AC5
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG B 2001

Chain	Residue
B	GLU1781
B	HOH2195
B	HOH2239
B	HOH2240
B	HOH2241
B	HOH2242

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site_id	AC6
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MG B 2002

Chain	Residue
A	HOH2254
A	HOH2343
B	GLU1856
B	HOH2212
B	HOH2322

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site_id	AC7
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CL B 2003

Chain	Residue
B	GLN1830
B	LYS1838
B	HOH2230
B	HOH2282

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site_id	AC8
Number of Residues	3
Details	BINDING SITE FOR RESIDUE CL B 2004

Chain	Residue
A	LYS1792
A	ILE1977
B	THR1789

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