Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004252 | molecular_function | serine-type endopeptidase activity |
| A | 0006508 | biological_process | proteolysis |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 A 301 |
| Chain | Residue |
| A | HIS37 |
| A | ARG37 |
| B | TYR5 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 A 302 |
| Chain | Residue |
| A | SER75 |
| A | ASN76 |
| A | ARG206 |
| A | HOH450 |
| A | HOH455 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 A 303 |
| Chain | Residue |
| A | THR23 |
| A | SER115 |
| A | ARG116 |
| A | HOH430 |
| A | HOH470 |
| A | PHE21 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 A 304 |
| Chain | Residue |
| A | LYS62 |
| A | LEU88 |
| A | GLN170 |
| A | PRO170 |
| A | HIS170 |
| A | HOH469 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL A 305 |
| Chain | Residue |
| A | LEU90 |
| A | HIS91 |
| A | LYS92 |
| A | TRP237 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE P6G A 306 |
| Chain | Residue |
| A | ASN74 |
| A | LEU150 |
| A | SER202 |
| A | HOH436 |
| site_id | AC7 |
| Number of Residues | 33 |
| Details | BINDING SITE FOR CHAIN B OF BICYCLIC PEPTIDE UK18-D-ABA INHIBITOR OF UPA |
| Chain | Residue |
| A | ARG35 |
| A | HIS37 |
| A | SER37 |
| A | THR39 |
| A | TYR40 |
| A | VAL41 |
| A | CYS42 |
| A | HIS57 |
| A | ILE60 |
| A | ASP60 |
| A | TYR60 |
| A | HIS99 |
| A | TYR127 |
| A | TYR151 |
| A | ARG166 |
| A | THR178 |
| A | ASP189 |
| A | SER190 |
| A | GLN192 |
| A | GLY193 |
| A | SER195 |
| A | GLY216 |
| A | GLY218 |
| A | CYS220 |
| A | GLY226 |
| A | SO4301 |
| A | HOH444 |
| A | HOH466 |
| A | HOH475 |
| B | HOH201 |
| B | HOH202 |
| B | HOH203 |
| B | HOH205 |
Functional Information from PROSITE/UniProt
| site_id | PS00134 |
| Number of Residues | 6 |
| Details | TRYPSIN_HIS Serine proteases, trypsin family, histidine active site. ISATHC |
| Chain | Residue | Details |
| A | ILE53-CYS58 | |
| site_id | PS00135 |
| Number of Residues | 12 |
| Details | TRYPSIN_SER Serine proteases, trypsin family, serine active site. DScqGDSGGPLV |
| Chain | Residue | Details |
| A | ASP189-VAL200 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 3 |
| Details | Active site: {"description":"Charge relay system"} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"9151681","evidenceCode":"ECO:0000269"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","featureId":"CAR_000026"} |
