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4JH4

Crystal Structure of FosB from Bacillus cereus with Nickel and Fosfomycin

Functional Information from GO Data
ChainGOidnamespacecontents
A0000287molecular_functionmagnesium ion binding
A0005737cellular_componentcytoplasm
A0016740molecular_functiontransferase activity
A0016765molecular_functiontransferase activity, transferring alkyl or aryl (other than methyl) groups
A0046677biological_processresponse to antibiotic
A0046872molecular_functionmetal ion binding
B0000287molecular_functionmagnesium ion binding
B0005737cellular_componentcytoplasm
B0016740molecular_functiontransferase activity
B0016765molecular_functiontransferase activity, transferring alkyl or aryl (other than methyl) groups
B0046677biological_processresponse to antibiotic
B0046872molecular_functionmetal ion binding
Functional Information from PDB Data
site_idAC1
Number of Residues4
DetailsBINDING SITE FOR RESIDUE NI A 201
ChainResidue
AHIS66
AGLU115
AFCN202
BHIS7

site_idAC2
Number of Residues13
DetailsBINDING SITE FOR RESIDUE FCN A 202
ChainResidue
AARG124
ANI201
AHOH365
AHOH367
BHIS7
BCYS9
BTRP46
BALA48
ATYR64
AHIS66
AARG94
ATYR105
AGLU115

site_idAC3
Number of Residues4
DetailsBINDING SITE FOR RESIDUE NI B 201
ChainResidue
AHIS7
BHIS66
BGLU115
BFCN202

site_idAC4
Number of Residues13
DetailsBINDING SITE FOR RESIDUE FCN B 202
ChainResidue
AHIS7
ACYS9
ATRP46
AALA48
BTYR64
BHIS66
BARG94
BTYR105
BGLU115
BARG124
BNI201
BHOH336
BHOH364

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues2
DetailsACT_SITE: Proton donor/acceptor => ECO:0000255|PROSITE-ProRule:PRU01163
ChainResidueDetails
AGLU115
BGLU115

site_idSWS_FT_FI2
Number of Residues6
DetailsBINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_01512
ChainResidueDetails
AHIS7
AHIS66
AGLU115
BHIS7
BHIS66
BGLU115

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PDB entries from 2024-11-13

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