4JFR
Crystal structure of anabolic ornithine carbamoyltransferase from Vibrio vulnificus in complex with carbamoyl phosphate
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004585 | molecular_function | ornithine carbamoyltransferase activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0006520 | biological_process | amino acid metabolic process |
| A | 0006526 | biological_process | L-arginine biosynthetic process |
| A | 0006591 | biological_process | ornithine metabolic process |
| A | 0008652 | biological_process | amino acid biosynthetic process |
| A | 0016597 | molecular_function | amino acid binding |
| A | 0016740 | molecular_function | transferase activity |
| A | 0016743 | molecular_function | carboxyl- or carbamoyltransferase activity |
| A | 0019240 | biological_process | citrulline biosynthetic process |
| A | 0042450 | biological_process | L-arginine biosynthetic process via ornithine |
| B | 0004585 | molecular_function | ornithine carbamoyltransferase activity |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0006520 | biological_process | amino acid metabolic process |
| B | 0006526 | biological_process | L-arginine biosynthetic process |
| B | 0006591 | biological_process | ornithine metabolic process |
| B | 0008652 | biological_process | amino acid biosynthetic process |
| B | 0016597 | molecular_function | amino acid binding |
| B | 0016740 | molecular_function | transferase activity |
| B | 0016743 | molecular_function | carboxyl- or carbamoyltransferase activity |
| B | 0019240 | biological_process | citrulline biosynthetic process |
| B | 0042450 | biological_process | L-arginine biosynthetic process via ornithine |
| C | 0004585 | molecular_function | ornithine carbamoyltransferase activity |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0006520 | biological_process | amino acid metabolic process |
| C | 0006526 | biological_process | L-arginine biosynthetic process |
| C | 0006591 | biological_process | ornithine metabolic process |
| C | 0008652 | biological_process | amino acid biosynthetic process |
| C | 0016597 | molecular_function | amino acid binding |
| C | 0016740 | molecular_function | transferase activity |
| C | 0016743 | molecular_function | carboxyl- or carbamoyltransferase activity |
| C | 0019240 | biological_process | citrulline biosynthetic process |
| C | 0042450 | biological_process | L-arginine biosynthetic process via ornithine |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE CP A 401 |
| Chain | Residue |
| A | SER57 |
| A | ARG320 |
| A | HOH575 |
| B | GLN84 |
| B | HOH572 |
| A | THR58 |
| A | ARG59 |
| A | THR60 |
| A | ARG108 |
| A | HIS135 |
| A | GLN138 |
| A | CYS275 |
| A | LEU276 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL A 402 |
| Chain | Residue |
| A | LEU13 |
| A | PHE134 |
| A | PRO136 |
| A | SER173 |
| site_id | AC3 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE CP B 401 |
| Chain | Residue |
| B | SER57 |
| B | THR58 |
| B | ARG59 |
| B | THR60 |
| B | ARG108 |
| B | HIS135 |
| B | GLN138 |
| B | CYS275 |
| B | LEU276 |
| B | ARG320 |
| C | GLN84 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CL B 402 |
| Chain | Residue |
| B | LEU13 |
| B | PHE134 |
| B | PRO136 |
| B | SER173 |
| B | HOH545 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL C 401 |
| Chain | Residue |
| C | LEU13 |
| C | PRO136 |
| C | SER173 |
| C | HOH534 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MG C 402 |
| Chain | Residue |
| C | GLY46 |
| C | HOH566 |
| C | HOH567 |
| C | HOH568 |
| C | HOH569 |
| C | HOH570 |
Functional Information from PROSITE/UniProt
| site_id | PS00097 |
| Number of Residues | 8 |
| Details | CARBAMOYLTRANSFERASE Aspartate and ornithine carbamoyltransferases signature. FeKaSTRT |
| Chain | Residue | Details |
| A | PHE53-THR60 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 24 |
| Details | Binding site: {"evidences":[{"source":"Reference","evidenceCode":"ECO:0000269","citation":{"citationType":"submission","publicationDate":"SEP-2012","submissionDatabase":"PDB data bank","title":"Structural studies of ornithine carbamoyltransferase from various pathogens.","authors":["Shabalin I.G.","Winsor J.","Grimshaw S.","Osinski T.","Chordia M.D.","Anderson W.F.","Minor W."]}},{"source":"Reference","evidenceCode":"ECO:0000269","citation":{"citationType":"submission","publicationDate":"FEB-2013","submissionDatabase":"PDB data bank","title":"Crystal structures and kinetic properties of anabolic ornithine carbamoyltransferase from human pathogens Vibrio vulnificus and Bacillus anthracis.","authors":["Shabalin I.G.","Winsor J.","Grimshaw S.","Minor W."]}},{"source":"PDB","id":"4H31","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4JFR","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4JHX","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4JQO","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 3 |
| Details | Binding site: {"evidences":[{"source":"Reference","evidenceCode":"ECO:0000269","citation":{"citationType":"submission","publicationDate":"SEP-2012","submissionDatabase":"PDB data bank","title":"Structural studies of ornithine carbamoyltransferase from various pathogens.","authors":["Shabalin I.G.","Winsor J.","Grimshaw S.","Osinski T.","Chordia M.D.","Anderson W.F.","Minor W."]}},{"source":"Reference","evidenceCode":"ECO:0000269","citation":{"citationType":"submission","publicationDate":"FEB-2013","submissionDatabase":"PDB data bank","title":"Crystal structures and kinetic properties of anabolic ornithine carbamoyltransferase from human pathogens Vibrio vulnificus and Bacillus anthracis.","authors":["Shabalin I.G.","Winsor J.","Grimshaw S.","Minor W."]}},{"source":"PDB","id":"4H31","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4JQO","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 12 |
| Details | Binding site: {"evidences":[{"source":"Reference","evidenceCode":"ECO:0000269","citation":{"citationType":"submission","publicationDate":"SEP-2012","submissionDatabase":"PDB data bank","title":"Structural studies of ornithine carbamoyltransferase from various pathogens.","authors":["Shabalin I.G.","Winsor J.","Grimshaw S.","Osinski T.","Chordia M.D.","Anderson W.F.","Minor W."]}},{"source":"Reference","evidenceCode":"ECO:0000269","citation":{"citationType":"submission","publicationDate":"FEB-2013","submissionDatabase":"PDB data bank","title":"Crystal structures and kinetic properties of anabolic ornithine carbamoyltransferase from human pathogens Vibrio vulnificus and Bacillus anthracis.","authors":["Shabalin I.G.","Winsor J.","Grimshaw S.","Minor W."]}},{"source":"PDB","id":"4H31","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4JHX","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4JQO","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
