4JCJ
Crystal structure of Isl1 LIM domains with Ldb1 LIM-interaction domain
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000981 | molecular_function | DNA-binding transcription factor activity, RNA polymerase II-specific |
| A | 0045944 | biological_process | positive regulation of transcription by RNA polymerase II |
| A | 0048665 | biological_process | neuron fate specification |
| B | 0000981 | molecular_function | DNA-binding transcription factor activity, RNA polymerase II-specific |
| B | 0045944 | biological_process | positive regulation of transcription by RNA polymerase II |
| B | 0048665 | biological_process | neuron fate specification |
| C | 0000981 | molecular_function | DNA-binding transcription factor activity, RNA polymerase II-specific |
| C | 0045944 | biological_process | positive regulation of transcription by RNA polymerase II |
| C | 0048665 | biological_process | neuron fate specification |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN A 401 |
| Chain | Residue |
| A | CYS17 |
| A | CYS20 |
| A | HIS39 |
| A | CYS42 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN A 402 |
| Chain | Residue |
| A | CYS45 |
| A | CYS48 |
| A | CYS67 |
| A | ASP70 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN A 403 |
| Chain | Residue |
| A | CYS82 |
| A | HIS101 |
| A | CYS104 |
| A | CYS79 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN A 404 |
| Chain | Residue |
| A | CYS107 |
| A | CYS110 |
| A | CYS129 |
| A | ASP132 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN B 401 |
| Chain | Residue |
| B | CYS107 |
| B | CYS110 |
| B | CYS129 |
| B | ASP132 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN B 402 |
| Chain | Residue |
| B | CYS17 |
| B | CYS20 |
| B | HIS39 |
| B | CYS42 |
| site_id | AC7 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN B 403 |
| Chain | Residue |
| B | CYS45 |
| B | CYS48 |
| B | CYS67 |
| B | ASP70 |
| site_id | AC8 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN B 404 |
| Chain | Residue |
| B | CYS79 |
| B | CYS82 |
| B | HIS101 |
| B | CYS104 |
| site_id | AC9 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN C 401 |
| Chain | Residue |
| C | CYS17 |
| C | CYS20 |
| C | HIS39 |
| C | CYS42 |
| site_id | BC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN C 402 |
| Chain | Residue |
| C | CYS45 |
| C | CYS48 |
| C | CYS67 |
| C | ASP70 |
| site_id | BC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN C 403 |
| Chain | Residue |
| C | CYS79 |
| C | CYS82 |
| C | HIS101 |
| C | CYS104 |
| site_id | BC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN C 404 |
| Chain | Residue |
| C | CYS107 |
| C | CYS110 |
| C | CYS129 |
| C | ASP132 |
Functional Information from PROSITE/UniProt
| site_id | PS00478 |
| Number of Residues | 36 |
| Details | LIM_DOMAIN_1 LIM zinc-binding domain signature. CvgCgnqihdqyilrvspdle....WHaaClkCaeCnqyL |
| Chain | Residue | Details |
| A | CYS17-LEU52 | |
| A | CYS79-LEU114 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 3 |
| Details | MOD_RES: Phosphoserine => ECO:0007744|PubMed:21183079 |
| Chain | Residue | Details |
| B | MET302 | |
| C | MET302 | |
| A | MET302 |
