4JB1

Crystal structure of P. aeruginosa MurB in complex with NADP+

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0008360	biological_process	regulation of cell shape
A	0008762	molecular_function	UDP-N-acetylmuramate dehydrogenase activity
A	0009252	biological_process	peptidoglycan biosynthetic process
A	0016491	molecular_function	oxidoreductase activity
A	0050660	molecular_function	flavin adenine dinucleotide binding
A	0051301	biological_process	cell division
A	0071555	biological_process	cell wall organization
A	0071949	molecular_function	FAD binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	30
Details	BINDING SITE FOR RESIDUE FAD A 401

Chain	Residue
A	VAL51
A	GLY119
A	THR120
A	ALA123
A	MET126
A	GLN127
A	ILE129
A	GLY130
A	ARG166
A	TRP177
A	ILE179
A	GLY53
A	ARG224
A	ALA237
A	GLY238
A	ASN337
A	TYR339
A	NAP402
A	HOH503
A	HOH514
A	HOH656
A	HOH660
A	GLY54
A	HOH661
A	GLY55
A	SER56
A	ASN57
A	LEU58
A	ILE117
A	PRO118

---

site_id	AC2
Number of Residues	25
Details	BINDING SITE FOR RESIDUE NAP A 402

Chain	Residue
A	ALA131
A	TYR132
A	ARG166
A	ASP195
A	TYR196
A	ARG224
A	LYS227
A	LEU228
A	SER239
A	ASN243
A	TYR264
A	LYS272
A	GLU335
A	FAD401
A	GOL407
A	HOH504
A	HOH509
A	HOH528
A	HOH530
A	HOH563
A	HOH602
A	HOH615
A	HOH616
A	HOH633
A	HOH652

---

site_id	AC3
Number of Residues	6
Details	BINDING SITE FOR RESIDUE GOL A 403

Chain	Residue
A	GLY269
A	GLY282
A	GLY283
A	TRP284
A	ASP323
A	ARG327

---

site_id	AC4
Number of Residues	10
Details	BINDING SITE FOR RESIDUE GOL A 404

Chain	Residue
A	GLY207
A	ILE208
A	ALA209
A	GLN312
A	ALA315
A	LEU316
A	ARG319
A	HOH579
A	HOH628
A	HOH645

---

site_id	AC5
Number of Residues	8
Details	BINDING SITE FOR RESIDUE GOL A 405

Chain	Residue
A	GLY110
A	VAL134
A	ASP138
A	VAL139
A	GLU190
A	HIS193
A	HOH582
A	HOH614

---

site_id	AC6
Number of Residues	8
Details	BINDING SITE FOR RESIDUE GOL A 406

Chain	Residue
A	LEU116
A	ARG225
A	LEU228
A	PRO229
A	ASP230
A	HOH527
A	HOH654
A	HOH655

---

site_id	AC7
Number of Residues	8
Details	BINDING SITE FOR RESIDUE GOL A 407

Chain	Residue
A	ALA131
A	TYR132
A	GLY133
A	VAL134
A	GLU135
A	ARG166
A	TYR196
A	NAP402

---

site_id	AC8
Number of Residues	7
Details	BINDING SITE FOR RESIDUE GOL A 408

Chain	Residue
A	GLN321
A	PRO334
A	LEU338
A	SER80
A	ASP81
A	ARG314
A	GLU318

---

Functional Information from PROSITE/UniProt

site_id	PS00430
Number of Residues	92
Details	TONB_DEPENDENT_REC_1 TonB-dependent receptor (TBDR) proteins signature 1. smslelqehcslkpyntfgidvrarllahardeadvrealalarerglpllvigggsnllltrdvealvlrmasqgrrivsdaa...............................DSVLVEAE

Chain	Residue	Details
A	SER0-GLU91

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	171
Details	Domain: {"description":"FAD-binding PCMH-type","evidences":[{"source":"HAMAP-Rule","id":"MF_00037","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	2
Details	Active site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00037","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	1
Details	Active site: {"description":"Proton donor","evidences":[{"source":"HAMAP-Rule","id":"MF_00037","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---