4JAM

Crystal structure of broadly neutralizing anti-hiv-1 antibody ch103

Functional Information from PDB Data

site_id	AC1
Number of Residues	7
Details	BINDING SITE FOR RESIDUE SO4 H 301

Chain	Residue
H	LYS143
H	ASP144
H	GLN171
H	HOH410
H	HOH489
H	HOH553
L	LYS129

---

site_id	AC2
Number of Residues	9
Details	BINDING SITE FOR RESIDUE SO4 H 302

Chain	Residue
A	HOH472
H	PRO123
H	LYS209
H	EDO309
H	HOH493
H	HOH533
L	GLU123
A	SER203
A	HOH442

---

site_id	AC3
Number of Residues	5
Details	BINDING SITE FOR RESIDUE SO4 H 303

Chain	Residue
H	GLY30
H	GLY31
H	HIS53
H	ARG97
H	HOH517

---

site_id	AC4
Number of Residues	8
Details	BINDING SITE FOR RESIDUE SO4 H 304

Chain	Residue
H	GLN171
H	SER172
H	HOH461
H	HOH541
H	HOH567
L	GLY158
L	GLU160
L	SER179

---

site_id	AC5
Number of Residues	5
Details	BINDING SITE FOR RESIDUE SO4 H 305

Chain	Residue
H	HIS164
H	HOH418
H	HOH531
L	GLN167
L	SER168

---

site_id	AC6
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 H 306

Chain	Residue
H	HIS53
H	THR73
H	HOH529
H	HOH539

---

site_id	AC7
Number of Residues	9
Details	BINDING SITE FOR RESIDUE EDO H 307

Chain	Residue
H	LYS143
H	GLN171
H	SER177
H	HOH461
H	HOH550
H	HOH553
L	TYR177
L	SER179
L	HOH448

---

site_id	AC8
Number of Residues	7
Details	BINDING SITE FOR RESIDUE EDO H 308

Chain	Residue
H	ALA84
H	ALA85
H	LEU170
H	GLN171
H	SER172
H	HOH512
L	GLU160

---

site_id	AC9
Number of Residues	8
Details	BINDING SITE FOR RESIDUE EDO H 309

Chain	Residue
A	HOH472
H	PRO123
H	ALA125
H	LYS210
H	GLU212
H	SO4302
H	HOH519
H	HOH577

---

site_id	BC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE EDO H 310

Chain	Residue
A	PRO119
A	VAL207
A	HOH403
H	SER120
H	VAL121
H	GOL312

---

site_id	BC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE EDO H 311

Chain	Residue
H	GLN99
H	LEU100
H	VAL100
L	TRP91

---

site_id	BC3
Number of Residues	11
Details	BINDING SITE FOR RESIDUE GOL H 312

Chain	Residue
A	GLY118
A	PRO119
A	SER203
A	THR205
A	HOH410
H	VAL121
H	PHE122
H	PRO123
H	LYS209
H	EDO310
L	GLU123

---

site_id	BC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 L 301

Chain	Residue
B	LYS110
H	LYS129
L	LYS204
L	HOH530

---

site_id	BC5
Number of Residues	7
Details	BINDING SITE FOR RESIDUE EDO L 302

Chain	Residue
L	TYR2
L	GLY25
L	ALA26
L	SER27
L	VAL90
L	ASP92
L	HOH466

---

site_id	BC6
Number of Residues	7
Details	BINDING SITE FOR RESIDUE SO4 A 301

Chain	Residue
H	LYS206
H	ASP208
A	LYS206
A	ASP208
A	HOH489
A	HOH537
B	HOH485

---

site_id	BC7
Number of Residues	5
Details	BINDING SITE FOR RESIDUE SO4 A 302

Chain	Residue
A	PRO123
A	LYS209
A	HOH460
A	HOH527
B	GLU123

---

site_id	BC8
Number of Residues	7
Details	BINDING SITE FOR RESIDUE SO4 A 303

Chain	Residue
A	LYS143
A	ASP144
A	GLN171
A	HOH440
A	HOH497
B	LYS129
B	SER179

---

site_id	BC9
Number of Residues	5
Details	BINDING SITE FOR RESIDUE EDO A 304

Chain	Residue
A	GLN99
A	LEU100
A	VAL100
A	HOH470
B	TRP91

---

site_id	CC1
Number of Residues	8
Details	BINDING SITE FOR RESIDUE EDO A 305

Chain	Residue
A	LYS143
A	GLN171
A	SER177
A	HOH531
A	HOH536
B	TYR177
B	HOH422
B	HOH472

---

site_id	CC2
Number of Residues	8
Details	BINDING SITE FOR RESIDUE EDO A 306

Chain	Residue
A	VAL163
A	HIS164
A	THR165
A	HOH532
B	SER24
B	GLY25
B	SER69
B	SO4304

---

site_id	CC3
Number of Residues	2
Details	BINDING SITE FOR RESIDUE EDO A 307

Chain	Residue
A	THR17
A	ARG81

---

site_id	CC4
Number of Residues	7
Details	BINDING SITE FOR RESIDUE SO4 B 301

Chain	Residue
B	ARG107
B	TYR140
B	LYS166
B	TYR172
B	HOH444
B	HOH496
B	HOH500

---

site_id	CC5
Number of Residues	8
Details	BINDING SITE FOR RESIDUE SO4 B 302

Chain	Residue
A	GLN171
A	SER172
B	GLY158
B	GLU160
B	HOH422
B	HOH429
B	HOH555
B	HOH561

---

site_id	CC6
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 B 303

Chain	Residue
A	TYR100
B	SER56
B	HOH497

---

site_id	CC7
Number of Residues	8
Details	BINDING SITE FOR RESIDUE SO4 B 304

Chain	Residue
A	HIS164
A	EDO306
B	SER69
B	THR70
B	LYS166
B	GLN167
B	SER168
B	HOH527

---

site_id	CC8
Number of Residues	5
Details	BINDING SITE FOR RESIDUE SO4 B 305

Chain	Residue
B	GLN184
B	HIS188
B	HOH483
B	HOH599
H	LYS201

---

site_id	CC9
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 B 306

Chain	Residue
B	LYS204
B	HOH512
B	HOH597
B	HOH623

---

site_id	DC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE EDO B 307

Chain	Residue
A	HOH538
B	ASP151
B	SER152
B	SER153
B	ARG189

---

site_id	DC2
Number of Residues	3
Details	BINDING SITE FOR RESIDUE EDO B 308

Chain	Residue
B	SER67
B	GLY68
B	LYS166

---

Functional Information from PROSITE/UniProt

site_id	PS00290
Number of Residues	7
Details	IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YICNVNH

Chain	Residue	Details
H	TYR194-HIS200
L	TYR191-HIS197

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