4J9M

Human DNA polymerase eta-DNA ternary complex: misincorporation G opposite T after an A at the primer 3' end (AA/G)

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003684	molecular_function	damaged DNA binding
A	0006281	biological_process	DNA repair

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MG A 501

Chain	Residue
A	ASP13
A	MET14
A	ASP115
A	MG502
A	XG4504

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site_id	AC2
Number of Residues	8
Details	BINDING SITE FOR RESIDUE MG A 502

Chain	Residue
A	XG4504
A	HOH609
A	HOH710
P	DA9
A	ASP13
A	ASP115
A	GLU116
A	MG501

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site_id	AC3
Number of Residues	3
Details	BINDING SITE FOR RESIDUE NA A 503

Chain	Residue
A	PRO27
A	HIS28
A	ARG30

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site_id	AC4
Number of Residues	25
Details	BINDING SITE FOR RESIDUE XG4 A 504

Chain	Residue
A	ASP13
A	MET14
A	ASP15
A	CYS16
A	PHE17
A	PHE18
A	GLN38
A	ILE48
A	ALA49
A	TYR52
A	ARG55
A	ARG61
A	ASP115
A	LYS231
A	MG501
A	MG502
A	HOH606
A	HOH607
A	HOH609
A	HOH625
A	HOH667
A	HOH710
P	DA9
T	DT4
T	DT5

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site_id	AC5
Number of Residues	8
Details	BINDING SITE FOR RESIDUE GOL A 505

Chain	Residue
A	GLN25
A	PRO244
A	SER248
A	GLY276
A	GLU277
A	HOH613
A	HOH636
A	HOH736

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site_id	AC6
Number of Residues	6
Details	BINDING SITE FOR RESIDUE GOL A 506

Chain	Residue
A	ARG93
A	VAL97
A	ARG111
A	PRO316
A	HOH664
A	HOH728

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"PubMed","id":"27284197","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5KFO","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"PubMed","id":"27284197","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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