Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

4J6W

Crystal structure of HFQ from Pseudomonas aeruginosa in complex with CTP

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003723	molecular_function	RNA binding
A	0005829	cellular_component	cytosol
A	0006355	biological_process	regulation of DNA-templated transcription
A	0006417	biological_process	regulation of translation
A	0009372	biological_process	quorum sensing
A	0043487	biological_process	regulation of RNA stability
A	0043609	biological_process	regulation of carbon utilization
A	0045974	biological_process	regulation of translation, ncRNA-mediated
B	0003723	molecular_function	RNA binding
B	0005829	cellular_component	cytosol
B	0006355	biological_process	regulation of DNA-templated transcription
B	0006417	biological_process	regulation of translation
B	0009372	biological_process	quorum sensing
B	0043487	biological_process	regulation of RNA stability
B	0043609	biological_process	regulation of carbon utilization
B	0045974	biological_process	regulation of translation, ncRNA-mediated
C	0003723	molecular_function	RNA binding
C	0005829	cellular_component	cytosol
C	0006355	biological_process	regulation of DNA-templated transcription
C	0006417	biological_process	regulation of translation
C	0009372	biological_process	quorum sensing
C	0043487	biological_process	regulation of RNA stability
C	0043609	biological_process	regulation of carbon utilization
C	0045974	biological_process	regulation of translation, ncRNA-mediated
D	0003723	molecular_function	RNA binding
D	0005829	cellular_component	cytosol
D	0006355	biological_process	regulation of DNA-templated transcription
D	0006417	biological_process	regulation of translation
D	0009372	biological_process	quorum sensing
D	0043487	biological_process	regulation of RNA stability
D	0043609	biological_process	regulation of carbon utilization
D	0045974	biological_process	regulation of translation, ncRNA-mediated
E	0003723	molecular_function	RNA binding
E	0005829	cellular_component	cytosol
E	0006355	biological_process	regulation of DNA-templated transcription
E	0006417	biological_process	regulation of translation
E	0009372	biological_process	quorum sensing
E	0043487	biological_process	regulation of RNA stability
E	0043609	biological_process	regulation of carbon utilization
E	0045974	biological_process	regulation of translation, ncRNA-mediated
F	0003723	molecular_function	RNA binding
F	0005829	cellular_component	cytosol
F	0006355	biological_process	regulation of DNA-templated transcription
F	0006417	biological_process	regulation of translation
F	0009372	biological_process	quorum sensing
F	0043487	biological_process	regulation of RNA stability
F	0043609	biological_process	regulation of carbon utilization
F	0045974	biological_process	regulation of translation, ncRNA-mediated

Functional Information from PDB Data

site_id	AC1
Number of Residues	12
Details	BINDING SITE FOR RESIDUE CTP A 101

Chain	Residue
A	TYR25
C	ARG69
E	ASN28
E	ILE30
A	GLY29
A	LYS31
A	THR61
A	HOH203
A	HOH221
A	HOH234
A	HOH244
A	HOH245

site_id	AC2
Number of Residues	17
Details	BINDING SITE FOR RESIDUE C5P A 102

Chain	Residue
A	HIS5
A	GLN8
A	GLN41
A	PHE42
A	LYS56
A	HOH233
A	HOH240
A	HOH250
A	HOH260
B	CTP101
B	HOH236
E	PHE42
E	HIS57
E	C5P101
E	MG104
E	MG105
E	HOH229

site_id	AC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG A 103

Chain	Residue
A	ASP9
A	PHE39
A	ASP40
A	LYS56

site_id	AC4
Number of Residues	2
Details	BINDING SITE FOR RESIDUE NA A 104

Chain	Residue
D	P6G103
D	HOH227

site_id	AC5
Number of Residues	30
Details	BINDING SITE FOR RESIDUE CTP B 101

Chain	Residue
A	PHE42
A	TYR55
A	HIS57
A	C5P102
A	HOH240
A	HOH260
B	HIS5
B	GLN8
B	GLN41
B	PHE42
B	LYS56
B	HIS57
B	MG102
B	HOH206
B	HOH220
B	HOH221
B	HOH222
B	HOH236
B	HOH237
B	HOH238
C	MG103
C	MG104
D	C5P101
D	MG105
D	HOH208
E	C5P101
E	MG105
E	HOH229
F	CDP101
F	HOH228

site_id	AC6
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MG B 102

Chain	Residue
B	CTP101
B	HOH222
B	HOH236
D	C5P101
D	HOH226

site_id	AC7
Number of Residues	12
Details	BINDING SITE FOR RESIDUE CTP C 101

Chain	Residue
C	TYR25
C	GLY29
C	LYS31
C	SER60
C	THR61
C	HOH202
C	HOH230
C	HOH236
C	HOH243
F	ASN28
F	ILE30
F	HOH202

site_id	AC8
Number of Residues	14
Details	BINDING SITE FOR RESIDUE C5P C 102

Chain	Residue
C	HIS5
C	GLN8
C	GLN41
C	PHE42
C	LYS56
C	MG103
C	MG104
C	HOH224
E	C5P101
F	PHE42
F	TYR55
F	HIS57
F	CDP101
F	NA105

site_id	AC9
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MG C 103

Chain	Residue
E	C5P101
F	CDP101
B	CTP101
C	C5P102
C	MG104

site_id	BC1
Number of Residues	8
Details	BINDING SITE FOR RESIDUE MG C 104

Chain	Residue
A	HOH260
B	CTP101
B	HOH237
C	C5P102
C	MG103
D	C5P101
F	CDP101
F	NA105

site_id	BC2
Number of Residues	17
Details	BINDING SITE FOR RESIDUE C5P D 101

Chain	Residue
B	PHE42
B	HIS57
B	CTP101
B	MG102
B	HOH237
C	MG104
D	HIS5
D	GLN8
D	GLN41
D	PHE42
D	LYS56
D	HIS57
D	MG104
D	MG105
D	HOH226
F	CDP101
F	NA105

site_id	BC3
Number of Residues	14
Details	BINDING SITE FOR RESIDUE CTP D 102

Chain	Residue
B	LEU26
B	ASN28
B	ILE30
B	HOH203
C	GLN35
C	ASN48
D	TYR25
D	GLY29
D	LYS31
D	SER60
D	THR61
D	HOH202
D	HOH219
D	HOH221

site_id	BC4
Number of Residues	6
Details	BINDING SITE FOR RESIDUE P6G D 103

Chain	Residue
A	NA104
B	VAL27
C	ARG66
D	VAL27
D	HOH227
F	VAL27

site_id	BC5
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MG D 104

Chain	Residue
D	PHE42
D	LYS56
D	HIS57
D	C5P101
F	CDP101

site_id	BC6
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG D 105

Chain	Residue
B	CTP101
B	HOH220
D	C5P101
F	CDP101

site_id	BC7
Number of Residues	20
Details	BINDING SITE FOR RESIDUE C5P E 101

Chain	Residue
A	C5P102
A	HOH233
A	HOH260
B	CTP101
C	PHE42
C	TYR55
C	HIS57
C	C5P102
C	MG103
C	HOH207
E	GLY4
E	GLN8
E	GLN41
E	PHE42
E	LYS56
E	HIS57
E	MG104
E	MG105
E	HOH204
E	HOH229

site_id	BC8
Number of Residues	14
Details	BINDING SITE FOR RESIDUE CTP E 102

Chain	Residue
C	ASN28
C	ILE30
C	HOH204
E	TYR25
E	GLY29
E	LYS31
E	SER60
E	THR61
E	HOH201
E	HOH209
E	HOH217
E	HOH227
E	HOH230
E	HOH237

site_id	BC9
Number of Residues	2
Details	BINDING SITE FOR RESIDUE CL E 103

Chain	Residue
E	LYS31
E	HOH230

site_id	CC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG E 104

Chain	Residue
A	C5P102
A	HOH233
A	HOH260
E	C5P101

site_id	CC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG E 105

Chain	Residue
A	C5P102
A	HOH249
B	CTP101
E	HIS57
E	C5P101
E	HOH229

site_id	CC3
Number of Residues	23
Details	BINDING SITE FOR RESIDUE CDP F 101

Chain	Residue
B	CTP101
B	HOH238
C	HIS57
C	C5P102
C	MG103
C	MG104
C	HOH224
D	PHE42
D	TYR55
D	HIS57
D	C5P101
D	MG104
D	MG105
F	GLY4
F	GLN8
F	GLN41
F	PHE42
F	LYS56
F	HIS57
F	NA105
F	HOH212
F	HOH228
F	HOH235

site_id	CC4
Number of Residues	11
Details	BINDING SITE FOR RESIDUE CTP F 102

Chain	Residue
C	ARG19
D	ASN28
D	ILE30
F	TYR25
F	GLY29
F	THR61
F	HOH204
F	HOH213
F	HOH233
F	HOH241
F	HOH249

site_id	CC5
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CL F 103

Chain	Residue
D	SER51
D	HOH218
F	PRO67
F	VAL68

site_id	CC6
Number of Residues	4
Details	BINDING SITE FOR RESIDUE NA F 104

Chain	Residue
E	GLU18
F	GLU18
F	VAL68
F	ARG69

site_id	CC7
Number of Residues	6
Details	BINDING SITE FOR RESIDUE NA F 105

Chain	Residue
B	HOH237
C	C5P102
C	MG104
C	HOH224
D	C5P101
F	CDP101

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	354
Details	Domain: {"description":"Sm","evidences":[{"source":"PROSITE-ProRule","id":"PRU01346","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)