4J6K

Crystal structure of calcium2+-free wild-type CD23 lectin domain (crystal form B)

Functional Information from PDB Data

site_id	AC1
Number of Residues	8
Details	BINDING SITE FOR RESIDUE SO4 D 301

Chain	Residue
A	ARG263
A	SER265
A	ARG267
A	HOH305
A	HOH326
D	SER254
D	GLN255
G	LYS229

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site_id	AC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE SO4 F 301

Chain	Residue
C	SER265
C	ARG267
F	SER254
F	GLN255
H	LYS229
C	ARG263

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site_id	AC3
Number of Residues	7
Details	BINDING SITE FOR RESIDUE SO4 G 301

Chain	Residue
B	ARG263
B	SER265
B	ARG267
B	HOH312
D	LYS229
G	SER254
G	GLN255

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site_id	AC4
Number of Residues	6
Details	BINDING SITE FOR RESIDUE SO4 H 301

Chain	Residue
E	ARG263
E	SER265
E	ARG267
F	LYS229
H	SER254
H	GLN255

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Functional Information from PROSITE/UniProt

site_id	PS00615
Number of Residues	24
Details	C_TYPE_LECTIN_1 C-type lectin domain signature. CVmmrgsgr.....WNDAFCdrklgaWVC

Chain	Residue	Details
A	CYS259-CYS282

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	32
Details	BINDING: BINDING => ECO:0000269|PubMed:16765898

Chain	Residue	Details
A	GLU249
C	THR251
C	ASN269
C	ASP270
D	GLU249
D	THR251
D	ASN269
D	ASP270
E	GLU249
E	THR251
E	ASN269
A	THR251
E	ASP270
F	GLU249
F	THR251
F	ASN269
F	ASP270
G	GLU249
G	THR251
G	ASN269
G	ASP270
H	GLU249
A	ASN269
H	THR251
H	ASN269
H	ASP270
A	ASP270
B	GLU249
B	THR251
B	ASN269
B	ASP270
C	GLU249

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site_id	SWS_FT_FI2
Number of Residues	8
Details	CARBOHYD: O-linked (Xyl...) (chondroitin sulfate) serine => ECO:0000269|PubMed:37453717

Chain	Residue	Details
A	SER296
B	SER296
C	SER296
D	SER296
E	SER296
F	SER296
G	SER296
H	SER296

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