Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| A | 0006508 | biological_process | proteolysis |
| B | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| B | 0006508 | biological_process | proteolysis |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 19 |
| Details | BINDING SITE FOR RESIDUE G52 A 201 |
| Chain | Residue |
| A | ASP25 |
| B | GLY27 |
| B | ALA28 |
| B | ASP29 |
| B | ASN30 |
| B | ILE32 |
| B | GLY48 |
| B | GLY49 |
| B | ILE50 |
| B | VAL82 |
| B | HOH1001 |
| A | GLY27 |
| A | ALA28 |
| A | ASP29 |
| A | ASN30 |
| A | GLY48 |
| A | ILE50 |
| A | VAL82 |
| B | ASP25 |
| site_id | AC2 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE IOD A 202 |
| site_id | AC3 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE IOD A 203 |
| site_id | AC4 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE IOD A 204 |
| site_id | AC5 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE IOD A 205 |
| Chain | Residue |
| A | THR12 |
| A | IOD206 |
| site_id | AC6 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE IOD A 206 |
| site_id | AC7 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE IOD A 207 |
| site_id | AC8 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE IOD A 208 |
| Chain | Residue |
| A | GLU21 |
| A | VAL82 |
| A | HOH340 |
| B | ARG8 |
| site_id | AC9 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE IOD A 209 |
| site_id | BC1 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE IOD A 210 |
| site_id | BC2 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE IOD A 211 |
| site_id | BC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE IOD A 212 |
| Chain | Residue |
| A | LYS14 |
| A | GLY16 |
| A | GLY17 |
| A | PRO63 |
| A | HOH344 |
| site_id | BC4 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE IOD A 214 |
| Chain | Residue |
| A | PRO44 |
| A | HOH338 |
| site_id | BC5 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE IOD A 215 |
| Chain | Residue |
| A | GLN61 |
| A | HOH341 |
| site_id | BC6 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE ACT A 216 |
| Chain | Residue |
| A | PHE53 |
| A | ARG57 |
| A | IOD204 |
| site_id | BC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE G52 B 101 |
| Chain | Residue |
| A | IOD203 |
| B | VAL56 |
| B | THR91 |
| B | GLY94 |
| B | HOH1024 |
| site_id | BC8 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE IOD B 102 |
| site_id | BC9 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE IOD B 103 |
| site_id | CC1 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE IOD B 106 |
| site_id | CC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE IOD B 107 |
| Chain | Residue |
| B | THR12 |
| B | HOH1041 |
| B | HOH1042 |
| site_id | CC3 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE IOD B 108 |
| site_id | CC4 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE IOD B 109 |
Functional Information from PROSITE/UniProt
| site_id | PS00141 |
| Number of Residues | 12 |
| Details | ASP_PROTEASE Eukaryotic and viral aspartyl proteases active site. ALLDTGADNTIF |
| Chain | Residue | Details |
| A | ALA22-PHE33 | |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| A | ASP25 | |
| B | ASP25 | |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | SITE: Cleavage; by viral protease => ECO:0000250 |
| Chain | Residue | Details |
| A | PHE99 | |
| B | PHE99 | |
