4J4H

PylD in complex with pyrroline-carboxy-lysine and NADH

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0008652	biological_process	amino acid biosynthetic process
A	0016491	molecular_function	oxidoreductase activity
B	0008652	biological_process	amino acid biosynthetic process
B	0016491	molecular_function	oxidoreductase activity
C	0008652	biological_process	amino acid biosynthetic process
C	0016491	molecular_function	oxidoreductase activity
D	0008652	biological_process	amino acid biosynthetic process
D	0016491	molecular_function	oxidoreductase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	30
Details	BINDING SITE FOR RESIDUE NAI A 901

Chain	Residue
A	ALA2
A	ASP173
A	ALA203
A	THR204
A	PRO205
A	CYS206
A	THR209
A	PRO224
A	ILE226
A	GLU245
A	PRO246
A	ASN121
A	1J1902
A	MG904
A	HOH1001
A	HOH1002
A	HOH1005
A	HOH1091
A	HOH1113
A	HOH1166
A	HOH1186
C	HOH1041
A	VAL147
C	HOH1058
A	GLY150
A	LYS151
A	VAL152
A	TYR170
A	ASP171
A	ALA172

---

site_id	AC2
Number of Residues	16
Details	BINDING SITE FOR RESIDUE 1J1 A 902

Chain	Residue
A	LEU3
A	LEU4
A	PRO52
A	VAL53
A	GLY58
A	ILE59
A	ILE60
A	PHE63
A	ALA103
A	NAI901
A	HOH1011
A	HOH1013
A	HOH1040
A	HOH1042
A	HOH1051
A	HOH1166

---

site_id	AC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE NA A 903

Chain	Residue
A	GLU202
A	THR204
A	CYS206
A	PRO227

---

site_id	AC4
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG A 904

Chain	Residue
A	TYR129
A	GLU245
A	LEU247
A	ILE249
A	GLY250
A	NAI901

---

site_id	AC5
Number of Residues	35
Details	BINDING SITE FOR RESIDUE NAI B 901

Chain	Residue
B	ALA2
B	ASN121
B	THR125
B	VAL147
B	GLY150
B	LYS151
B	VAL152
B	TYR170
B	ASP171
B	ALA172
B	LEU176
B	ALA203
B	THR204
B	PRO205
B	CYS206
B	THR209
B	PRO224
B	ILE226
B	GLU245
B	PRO246
B	LEU247
B	1J1902
B	MG904
B	HOH1001
B	HOH1003
B	HOH1036
B	HOH1042
B	HOH1082
B	HOH1105
B	HOH1125
B	HOH1128
B	HOH1142
B	HOH1155
B	HOH1163
B	HOH1165

---

site_id	AC6
Number of Residues	14
Details	BINDING SITE FOR RESIDUE 1J1 B 902

Chain	Residue
B	NAI901
B	HOH1006
B	HOH1017
B	HOH1022
B	HOH1077
B	HOH1081
B	LEU3
B	LEU4
B	VAL53
B	GLY58
B	ILE59
B	ILE60
B	PHE63
B	ALA103

---

site_id	AC7
Number of Residues	4
Details	BINDING SITE FOR RESIDUE NA B 903

Chain	Residue
B	GLU202
B	THR204
B	CYS206
B	PRO227

---

site_id	AC8
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG B 904

Chain	Residue
B	TYR129
B	GLU245
B	LEU247
B	ILE249
B	GLY250
B	NAI901

---

site_id	AC9
Number of Residues	30
Details	BINDING SITE FOR RESIDUE NAI C 901

Chain	Residue
C	MET1
C	ALA2
C	ASN121
C	VAL147
C	GLY148
C	GLY150
C	LYS151
C	VAL152
C	TYR170
C	ASP171
C	ALA172
C	ASP173
C	LEU176
C	ALA203
C	THR204
C	PRO205
C	CYS206
C	THR209
C	PRO224
C	ILE226
C	GLU245
C	PRO246
C	1J1902
C	MG904
C	HOH1001
C	HOH1002
C	HOH1006
C	HOH1017
C	HOH1022
C	HOH1024

---

site_id	BC1
Number of Residues	15
Details	BINDING SITE FOR RESIDUE 1J1 C 902

Chain	Residue
C	LEU3
C	LEU4
C	PRO52
C	VAL53
C	GLY58
C	ILE59
C	ILE60
C	PHE63
C	ALA103
C	NAI901
C	HOH1004
C	HOH1013
C	HOH1015
C	HOH1016
C	HOH1021

---

site_id	BC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE NA C 903

Chain	Residue
C	GLU202
C	THR204
C	CYS206
C	PRO227

---

site_id	BC3
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG C 904

Chain	Residue
C	TYR129
C	GLU245
C	LEU247
C	ILE249
C	GLY250
C	NAI901

---

site_id	BC4
Number of Residues	29
Details	BINDING SITE FOR RESIDUE NAI D 901

Chain	Residue
B	HOH1124
B	HOH1130
D	MET1
D	ALA2
D	ASN121
D	VAL147
D	GLY150
D	LYS151
D	VAL152
D	TYR170
D	ASP171
D	ALA172
D	ALA203
D	THR204
D	PRO205
D	CYS206
D	THR209
D	PRO224
D	ILE226
D	GLU245
D	PRO246
D	1J1902
D	MG904
D	HOH1001
D	HOH1005
D	HOH1009
D	HOH1024
D	HOH1025
D	HOH1040

---

site_id	BC5
Number of Residues	15
Details	BINDING SITE FOR RESIDUE 1J1 D 902

Chain	Residue
D	LEU4
D	PRO52
D	VAL53
D	GLY58
D	ILE59
D	ILE60
D	PHE63
D	ALA103
D	ASP104
D	NAI901
D	HOH1002
D	HOH1003
D	HOH1006
D	HOH1014
D	HOH1036

---

site_id	BC6
Number of Residues	4
Details	BINDING SITE FOR RESIDUE NA D 903

Chain	Residue
D	GLU202
D	THR204
D	CYS206
D	PRO227

---

site_id	BC7
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG D 904

Chain	Residue
D	TYR129
D	GLU245
D	LEU247
D	ILE249
D	GLY250
D	NAI901

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	16
Details	BINDING: BINDING => ECO:0000269|PubMed:24916332, ECO:0007744|PDB:4Q39

Chain	Residue	Details
A	LEU4
C	VAL53
C	ILE60
C	ALA103
D	LEU4
D	VAL53
D	ILE60
D	ALA103
A	VAL53
A	ILE60
A	ALA103
B	LEU4
B	VAL53
B	ILE60
B	ALA103
C	LEU4

---

site_id	SWS_FT_FI2
Number of Residues	28
Details	BINDING: BINDING => ECO:0000269|PubMed:23720358, ECO:0000269|PubMed:24916332, ECO:0007744|PDB:4JK3, ECO:0007744|PDB:4Q3D

Chain	Residue	Details
A	LYS151
B	ASP171
B	CYS206
B	PRO224
B	ILE226
B	GLU245
C	LYS151
C	VAL152
C	ASP171
C	CYS206
C	PRO224
A	VAL152
C	ILE226
C	GLU245
D	LYS151
D	VAL152
D	ASP171
D	CYS206
D	PRO224
D	ILE226
D	GLU245
A	ASP171
A	CYS206
A	PRO224
A	ILE226
A	GLU245
B	LYS151
B	VAL152

---