Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

4J3I

X-ray crystal structure of bromodomain complex to 1.24 A resolution

Functional Information from PDB Data
site_idAC1
Number of Residues17
DetailsBINDING SITE FOR RESIDUE 1K0 A 201
ChainResidue
APRO82
AHOH301
AHOH327
AHOH349
AHOH352
AHOH469
AHOH487
AHOH498
AHOH503
APHE83
AVAL87
ALEU92
ALEU94
AASN140
AASP144
AILE146
AEDO202

site_idAC2
Number of Residues7
DetailsBINDING SITE FOR RESIDUE EDO A 202
ChainResidue
ATRP81
ALYS99
AMET149
A1K0201
AHOH316
AHOH339
AHOH349

site_idAC3
Number of Residues6
DetailsBINDING SITE FOR RESIDUE EDO A 203
ChainResidue
AILE100
AILE101
ALYS102
ATHR103
AASN135
AHOH539

site_idAC4
Number of Residues5
DetailsBINDING SITE FOR RESIDUE NA A 204
ChainResidue
APRO86
AVAL87
ATYR98
AHOH303
AHOH307

Functional Information from PROSITE/UniProt
site_idPS00633
Number of Residues60
DetailsBROMODOMAIN_1 Bromodomain signature. AwpFqqpvDavklnlpDYYkiIktpMdmgtIkkrlenny..Ywnaqeciqdfnt.MftNCyiY
ChainResidueDetails
AALA80-TYR139

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues1
DetailsSITE: Acetylated histone binding => ECO:0000269|PubMed:22464331
ChainResidueDetails
AASN140

site_idSWS_FT_FI2
Number of Residues2
DetailsCROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) => ECO:0007744|PubMed:28112733
ChainResidueDetails
ALYS99

222926

PDB entries from 2024-07-24

PDB statisticsPDBj update infoContact PDBjnumon