4J19

Structure of a novel telomere repeat binding protein bound to DNA

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003677	molecular_function	DNA binding
A	0003691	molecular_function	double-stranded telomeric DNA binding
B	0003677	molecular_function	DNA binding
B	0003691	molecular_function	double-stranded telomeric DNA binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CL C 101

Chain	Residue
A	LYS335
A	HOH416
C	DG13
D	HOH112

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	148
Details	DNA_BIND: Homeobox => ECO:0000255|PROSITE-ProRule:PRU00108, ECO:0000269|PubMed:23685356

Chain	Residue	Details
A	ARG267-ALA341
B	ARG267-ALA341

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site_id	SWS_FT_FI2
Number of Residues	2
Details	SITE: Critical for recognition and binding of 5'-TTAGGG-3' motifs in telomeric DNA => ECO:0000269|PubMed:23685356

Chain	Residue	Details
A	LYS335
B	LYS335

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site_id	SWS_FT_FI3
Number of Residues	4
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) => ECO:0007744|PubMed:28112733

Chain	Residue	Details
A	LYS310
B	LYS310

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