4J07
Crystal structure of a PROBABLE RIBOFLAVIN SYNTHASE, BETA CHAIN RIBH (6,7-dimethyl-8-ribityllumazine synthase, DMRL synthase, Lumazine synthase) from Mycobacterium leprae
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000906 | molecular_function | 6,7-dimethyl-8-ribityllumazine synthase activity |
| A | 0005829 | cellular_component | cytosol |
| A | 0009231 | biological_process | riboflavin biosynthetic process |
| A | 0009349 | cellular_component | riboflavin synthase complex |
| A | 0016740 | molecular_function | transferase activity |
| B | 0000906 | molecular_function | 6,7-dimethyl-8-ribityllumazine synthase activity |
| B | 0005829 | cellular_component | cytosol |
| B | 0009231 | biological_process | riboflavin biosynthetic process |
| B | 0009349 | cellular_component | riboflavin synthase complex |
| B | 0016740 | molecular_function | transferase activity |
| C | 0000906 | molecular_function | 6,7-dimethyl-8-ribityllumazine synthase activity |
| C | 0005829 | cellular_component | cytosol |
| C | 0009231 | biological_process | riboflavin biosynthetic process |
| C | 0009349 | cellular_component | riboflavin synthase complex |
| C | 0016740 | molecular_function | transferase activity |
| D | 0000906 | molecular_function | 6,7-dimethyl-8-ribityllumazine synthase activity |
| D | 0005829 | cellular_component | cytosol |
| D | 0009231 | biological_process | riboflavin biosynthetic process |
| D | 0009349 | cellular_component | riboflavin synthase complex |
| D | 0016740 | molecular_function | transferase activity |
| E | 0000906 | molecular_function | 6,7-dimethyl-8-ribityllumazine synthase activity |
| E | 0005829 | cellular_component | cytosol |
| E | 0009231 | biological_process | riboflavin biosynthetic process |
| E | 0009349 | cellular_component | riboflavin synthase complex |
| E | 0016740 | molecular_function | transferase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE NA A 201 |
| Chain | Residue |
| A | ALA70 |
| A | HIS73 |
| A | THR110 |
| A | HOH327 |
| A | HOH363 |
| A | HOH375 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE SO4 A 202 |
| Chain | Residue |
| A | HOH309 |
| A | HOH340 |
| B | ARG128 |
| D | LYS123 |
| A | GLY85 |
| A | ASP86 |
| A | THR87 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE NA B 201 |
| Chain | Residue |
| B | ALA70 |
| B | HIS73 |
| B | THR110 |
| B | HOH344 |
| B | HOH353 |
| B | HOH366 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 B 202 |
| Chain | Residue |
| B | ASP86 |
| B | THR87 |
| B | HOH345 |
| C | LYS123 |
| E | ARG128 |
| E | HOH327 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE NA C 201 |
| Chain | Residue |
| C | ALA70 |
| C | HIS73 |
| C | THR110 |
| C | HOH309 |
| C | HOH328 |
| C | HOH393 |
| site_id | AC6 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE SO4 C 202 |
| Chain | Residue |
| B | LYS123 |
| C | GLY85 |
| C | ASP86 |
| C | THR87 |
| C | HOH347 |
| C | HOH369 |
| D | ARG128 |
| D | HOH384 |
| site_id | AC7 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 D 201 |
| Chain | Residue |
| A | LYS123 |
| A | ARG128 |
| D | ASP86 |
| D | THR87 |
| D | HOH357 |
| D | HOH370 |
| site_id | AC8 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE SO4 D 202 |
| Chain | Residue |
| A | ASN95 |
| A | GLN99 |
| B | ASN95 |
| C | ASN95 |
| C | GLN99 |
| D | ASN95 |
| D | GLN99 |
| E | ASN95 |
| E | GLN99 |
| site_id | AC9 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE NA D 203 |
| Chain | Residue |
| D | ALA70 |
| D | HIS73 |
| D | THR110 |
| D | HOH326 |
| D | HOH329 |
| D | HOH334 |
| site_id | BC1 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE SO4 E 201 |
| Chain | Residue |
| C | ARG128 |
| E | GLY85 |
| E | ASP86 |
| E | THR87 |
| E | LYS123 |
| E | HOH324 |
| E | HOH343 |
| site_id | BC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE NA E 202 |
| Chain | Residue |
| E | ALA70 |
| E | HIS73 |
| E | THR110 |
| E | HOH316 |
| E | HOH328 |
| E | HOH369 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 5 |
| Details | Active site: {"description":"Proton donor","evidences":[{"source":"HAMAP-Rule","id":"MF_00178","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 40 |
| Details | Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00178","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
