4IVG
Crystal structure of mitochondrial Hsp90 (TRAP1) NTD-Middle domain dimer with AMPPNP
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000287 | molecular_function | magnesium ion binding |
| A | 0005509 | molecular_function | calcium ion binding |
| A | 0005524 | molecular_function | ATP binding |
| A | 0005739 | cellular_component | mitochondrion |
| A | 0005743 | cellular_component | mitochondrial inner membrane |
| A | 0006457 | biological_process | protein folding |
| A | 0016887 | molecular_function | ATP hydrolysis activity |
| A | 0019901 | molecular_function | protein kinase binding |
| A | 0042802 | molecular_function | identical protein binding |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0051082 | molecular_function | unfolded protein binding |
| A | 0140662 | molecular_function | ATP-dependent protein folding chaperone |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 27 |
| Details | BINDING SITE FOR RESIDUE ANP A 801 |
| Chain | Residue |
| A | GLU130 |
| A | GLN215 |
| A | PHE216 |
| A | GLY217 |
| A | VAL218 |
| A | GLY219 |
| A | PHE220 |
| A | THR266 |
| A | ARG417 |
| A | MG803 |
| A | HOH901 |
| A | ASN134 |
| A | HOH906 |
| A | HOH914 |
| A | HOH919 |
| A | HOH920 |
| A | HOH921 |
| A | HOH993 |
| A | HOH1010 |
| A | HOH1122 |
| A | ALA138 |
| A | ASP173 |
| A | MET178 |
| A | ASN186 |
| A | SER193 |
| A | GLY194 |
| A | GLY214 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE PO4 A 802 |
| Chain | Residue |
| A | LYS166 |
| A | ARG436 |
| A | ARG439 |
| A | HOH1167 |
| A | HOH1184 |
| A | HOH1192 |
| A | HOH1216 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE MG A 803 |
| Chain | Residue |
| A | ASN134 |
| A | ANP801 |
| A | HOH906 |
| A | HOH1122 |
