4IVF
Crystal structure of glutathione transferase homolog from Lodderomyces elongisporus, target EFI-501753, with two GSH per subunit
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0006749 | biological_process | glutathione metabolic process |
| B | 0006749 | biological_process | glutathione metabolic process |
| C | 0006749 | biological_process | glutathione metabolic process |
| D | 0006749 | biological_process | glutathione metabolic process |
| E | 0006749 | biological_process | glutathione metabolic process |
| F | 0006749 | biological_process | glutathione metabolic process |
| G | 0006749 | biological_process | glutathione metabolic process |
| H | 0006749 | biological_process | glutathione metabolic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE GSH A 301 |
| Chain | Residue |
| A | ASN17 |
| A | HOH424 |
| A | HOH449 |
| A | HOH529 |
| F | ARG142 |
| F | HOH478 |
| A | ARG57 |
| A | GLY119 |
| A | PRO120 |
| A | GLY123 |
| A | TRP184 |
| A | GSH302 |
| A | HOH412 |
| A | HOH423 |
| site_id | AC2 |
| Number of Residues | 16 |
| Details | BINDING SITE FOR RESIDUE GSH A 302 |
| Chain | Residue |
| A | THR15 |
| A | ASN17 |
| A | THR44 |
| A | LYS45 |
| A | ARG57 |
| A | ILE58 |
| A | PRO59 |
| A | GLN77 |
| A | THR78 |
| A | GSH301 |
| A | HOH411 |
| A | HOH412 |
| A | HOH415 |
| A | HOH426 |
| A | HOH549 |
| F | GLU117 |
| site_id | AC3 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE GSH B 301 |
| Chain | Residue |
| B | ASN17 |
| B | ARG57 |
| B | GLY119 |
| B | PRO120 |
| B | GLY123 |
| B | TRP184 |
| B | GSH302 |
| B | HOH406 |
| B | HOH411 |
| B | HOH446 |
| G | ARG142 |
| site_id | AC4 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE GSH B 302 |
| Chain | Residue |
| B | THR15 |
| B | ASN17 |
| B | LEU39 |
| B | THR44 |
| B | ARG57 |
| B | ILE58 |
| B | GLN77 |
| B | THR78 |
| B | GSH301 |
| B | HOH404 |
| B | HOH421 |
| B | HOH480 |
| G | GLU117 |
| site_id | AC5 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE GSH C 301 |
| Chain | Residue |
| C | ASN17 |
| C | ARG57 |
| C | GLY119 |
| C | PRO120 |
| C | GLY123 |
| C | TRP184 |
| C | GSH302 |
| C | HOH411 |
| C | HOH414 |
| C | HOH421 |
| C | HOH422 |
| C | HOH524 |
| D | ARG142 |
| D | HOH437 |
| site_id | AC6 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE GSH C 302 |
| Chain | Residue |
| C | THR15 |
| C | ASN17 |
| C | THR44 |
| C | LYS45 |
| C | ARG57 |
| C | ILE58 |
| C | GLN77 |
| C | THR78 |
| C | GSH301 |
| C | HOH402 |
| C | HOH403 |
| C | HOH408 |
| C | HOH421 |
| D | GLU117 |
| site_id | AC7 |
| Number of Residues | 15 |
| Details | BINDING SITE FOR RESIDUE GSH D 301 |
| Chain | Residue |
| C | ARG142 |
| D | ASN17 |
| D | ARG57 |
| D | GLY119 |
| D | PRO120 |
| D | GLY123 |
| D | TRP184 |
| D | GSH302 |
| D | HOH422 |
| D | HOH426 |
| D | HOH434 |
| D | HOH454 |
| D | HOH488 |
| D | HOH507 |
| D | HOH514 |
| site_id | AC8 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE GSH D 302 |
| Chain | Residue |
| D | ASN17 |
| D | LEU39 |
| D | LYS45 |
| D | ARG57 |
| D | ILE58 |
| D | GLN77 |
| D | THR78 |
| D | GSH301 |
| D | HOH401 |
| D | HOH413 |
| D | HOH453 |
| C | GLU117 |
| D | THR15 |
| site_id | AC9 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE CIT E 301 |
| Chain | Residue |
| E | PRO14 |
| E | THR15 |
| E | ASN126 |
| E | PHE130 |
| E | ARG187 |
| E | ARG190 |
| E | LYS223 |
| E | GSH302 |
| E | HOH422 |
| E | HOH451 |
| E | HOH563 |
| F | GLU192 |
| site_id | BC1 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE GSH E 302 |
| Chain | Residue |
| E | ASN17 |
| E | ARG57 |
| E | GLY119 |
| E | PRO120 |
| E | GLY123 |
| E | TRP184 |
| E | CIT301 |
| E | GSH303 |
| E | HOH409 |
| E | HOH414 |
| E | HOH415 |
| E | HOH426 |
| H | ARG142 |
| H | HOH471 |
| site_id | BC2 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE GSH E 303 |
| Chain | Residue |
| E | THR15 |
| E | ASN17 |
| E | THR44 |
| E | LYS45 |
| E | ARG57 |
| E | ILE58 |
| E | GLN77 |
| E | THR78 |
| E | GSH302 |
| E | HOH403 |
| E | HOH405 |
| E | HOH408 |
| E | HOH409 |
| H | GLU117 |
| site_id | BC3 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE GSH F 301 |
| Chain | Residue |
| A | ARG142 |
| F | ASN17 |
| F | ARG57 |
| F | GLY119 |
| F | PRO120 |
| F | GLY123 |
| F | HIS127 |
| F | TRP184 |
| F | GSH302 |
| F | HOH403 |
| F | HOH404 |
| F | HOH413 |
| F | HOH453 |
| site_id | BC4 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE GSH F 302 |
| Chain | Residue |
| A | GLU117 |
| F | THR15 |
| F | ASN17 |
| F | THR44 |
| F | LYS45 |
| F | ARG57 |
| F | ILE58 |
| F | GLN77 |
| F | THR78 |
| F | GSH301 |
| F | HOH407 |
| F | HOH427 |
| F | HOH486 |
| F | HOH535 |
| site_id | BC5 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE GSH G 301 |
| Chain | Residue |
| B | ARG142 |
| G | ASN17 |
| G | ARG57 |
| G | GLY119 |
| G | PRO120 |
| G | GLY123 |
| G | TRP184 |
| G | GSH302 |
| G | HOH414 |
| G | HOH419 |
| G | HOH445 |
| site_id | BC6 |
| Number of Residues | 16 |
| Details | BINDING SITE FOR RESIDUE GSH G 302 |
| Chain | Residue |
| B | GLU117 |
| G | THR15 |
| G | ASN17 |
| G | LEU39 |
| G | THR44 |
| G | LYS45 |
| G | ARG57 |
| G | ILE58 |
| G | PRO59 |
| G | GLN77 |
| G | THR78 |
| G | GSH301 |
| G | HOH404 |
| G | HOH411 |
| G | HOH414 |
| G | HOH425 |
| site_id | BC7 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE GSH H 301 |
| Chain | Residue |
| E | ARG142 |
| H | ASN17 |
| H | ARG57 |
| H | GLY119 |
| H | PRO120 |
| H | GLY123 |
| H | TRP184 |
| H | GSH302 |
| H | HOH415 |
| H | HOH420 |
| H | HOH423 |
| H | HOH431 |
| H | HOH470 |
| site_id | BC8 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE GSH H 302 |
| Chain | Residue |
| E | GLU117 |
| H | THR15 |
| H | ASN17 |
| H | LEU39 |
| H | THR44 |
| H | LYS45 |
| H | ARG57 |
| H | ILE58 |
| H | GLN77 |
| H | THR78 |
| H | GSH301 |
| H | HOH443 |
| H | HOH452 |
