Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004222 | molecular_function | metalloendopeptidase activity |
| A | 0006508 | biological_process | proteolysis |
| A | 0008237 | molecular_function | metallopeptidase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN A 701 |
| Chain | Residue |
| A | HIS477 |
| A | HIS481 |
| A | GLU537 |
| A | CIT702 |
| site_id | AC2 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE CIT A 702 |
| Chain | Residue |
| A | HIS481 |
| A | GLU537 |
| A | TRP572 |
| A | HIS590 |
| A | ARG596 |
| A | ZN701 |
| A | NA703 |
| A | HOH1033 |
| A | HOH1057 |
| A | ASN436 |
| A | ALA437 |
| A | ILE452 |
| A | HIS477 |
| A | GLU478 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE NA A 703 |
| Chain | Residue |
| A | CIT702 |
| A | HOH964 |
| A | HOH1187 |
| site_id | AC4 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE SO4 A 704 |
| Chain | Residue |
| A | THR58 |
| A | ARG522 |
| A | GLN602 |
| A | TYR620 |
| A | ARG621 |
| A | LYS625 |
| A | HOH880 |
| A | HOH1036 |
| A | HOH1054 |
| A | HOH1142 |
| A | HOH1233 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 A 705 |
| Chain | Residue |
| A | SER305 |
| A | TRP306 |
| A | HOH961 |
| A | HOH1018 |
| A | HOH1155 |
| A | HOH1185 |
| site_id | AC6 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CO3 A 706 |
| Chain | Residue |
| A | ARG102 |
| A | SER103 |
| A | ASN498 |
| site_id | AC7 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CO3 A 707 |
| Chain | Residue |
| A | THR97 |
| A | THR463 |
| A | ARG464 |
| A | HOH1162 |
| site_id | AC8 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CO3 A 708 |
| Chain | Residue |
| A | ASP152 |
| A | HOH1252 |
| site_id | AC9 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CO3 A 709 |
| Chain | Residue |
| A | LYS575 |
| A | HOH1034 |
| A | HOH1254 |
| site_id | BC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CO3 A 710 |
| Chain | Residue |
| A | ARG580 |
| A | VAL584 |
| A | CO3715 |
| A | HOH995 |
| site_id | BC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CO3 A 711 |
| Chain | Residue |
| A | TRP359 |
| A | LEU360 |
| A | SER361 |
| A | TRP462 |
| site_id | BC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CO3 A 712 |
| Chain | Residue |
| A | ASP8 |
| A | ALA56 |
| A | GLY618 |
| A | HOH1233 |
| site_id | BC4 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE CO3 A 713 |
| Chain | Residue |
| A | ARG287 |
| A | SER304 |
| A | HIS309 |
| A | HOH971 |
| A | HOH985 |
| A | HOH1114 |
| A | HOH1235 |
| site_id | BC5 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CO3 A 714 |
| Chain | Residue |
| A | GLU355 |
| A | LYS365 |
| A | HOH1001 |
| site_id | BC6 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CO3 A 715 |
| Chain | Residue |
| A | GLN587 |
| A | CO3710 |
| A | HOH1396 |
| site_id | BC7 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CO3 A 716 |
| Chain | Residue |
| A | PRO240 |
| A | ALA241 |
| A | LEU419 |
| A | HOH1025 |
| A | HOH1084 |
| A | HOH1393 |
| site_id | BC8 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE OXD A 717 |
| Chain | Residue |
| A | ARG5 |
| A | ARG370 |
| A | HOH957 |
Functional Information from PROSITE/UniProt
| site_id | PS00142 |
| Number of Residues | 10 |
| Details | ZINC_PROTEASE Neutral zinc metallopeptidases, zinc-binding region signature. TIGHEISHSF |
| Chain | Residue | Details |
| A | THR474-PHE483 | |
