4IUT

crystal structure of SHH1 SAWADEE domain in complex with H3K9me2 peptide

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003682	molecular_function	chromatin binding
B	0003682	molecular_function	chromatin binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN A 301

Chain	Residue
A	CYS191
A	HIS225
A	CYS230
A	CYS232

---

site_id	AC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CVM A 302

Chain	Residue
A	PHE145
A	VAL175
A	VAL179
A	HOH409

---

site_id	AC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN B 301

Chain	Residue
B	HIS225
B	CYS230
B	CYS232
B	CYS191

---

site_id	AC4
Number of Residues	7
Details	BINDING SITE FOR RESIDUE CVM B 302

Chain	Residue
B	PHE129
B	PHE145
B	VAL175
B	LYS176
B	VAL179
B	ARG180
B	GLU181

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	212
Details	Region: {"description":"SAWADEE domain"}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	8
Details	Binding site: {}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	1
Details	Modified residue: {"description":"N6-methyllysine; alternate","evidences":[{"source":"PubMed","id":"12581305","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"14712277","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"15598823","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"16258034","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	1
Details	Modified residue: {"description":"N6-methyllysine; alternate","evidences":[{"source":"PubMed","id":"12456661","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"12581305","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"14712277","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"15014946","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"15598823","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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