4ITN

Crystal structure of "compact P-loop" LpxK from Aquifex aeolicus in complex with chloride at 2.2 angstrom resolution

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0005524	molecular_function	ATP binding
A	0005886	cellular_component	plasma membrane
A	0006629	biological_process	lipid metabolic process
A	0009029	molecular_function	lipid-A 4'-kinase activity
A	0009244	biological_process	lipopolysaccharide core region biosynthetic process
A	0009245	biological_process	lipid A biosynthetic process
A	0016301	molecular_function	kinase activity
A	0016740	molecular_function	transferase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE GOL A 401

Chain	Residue
A	GLY287
A	GLU289
A	HOH561
A	HOH571

---

site_id	AC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE EPE A 402

Chain	Residue
A	ARG72
A	GLN142
A	HIS143
A	HOH508
A	HOH564

---

site_id	AC3
Number of Residues	3
Details	BINDING SITE FOR RESIDUE GOL A 403

Chain	Residue
A	ASP237
A	THR278
A	HOH541

---

site_id	AC4
Number of Residues	2
Details	BINDING SITE FOR RESIDUE GOL A 404

Chain	Residue
A	MET56
A	ASN295

---

site_id	AC5
Number of Residues	1
Details	BINDING SITE FOR RESIDUE GOL A 405

Chain	Residue
A	TYR315

---

site_id	AC6
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CL A 406

Chain	Residue
A	ASN43
A	GLY48
A	GLY50
A	LYS51
A	HOH501

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	7
Details	Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00409","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---