4IT9
Structure of Bacterial Enzyme
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0004030 | molecular_function | aldehyde dehydrogenase [NAD(P)+] activity |
| A | 0004777 | molecular_function | succinate-semialdehyde dehydrogenase (NAD+) activity |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0016620 | molecular_function | oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0004030 | molecular_function | aldehyde dehydrogenase [NAD(P)+] activity |
| B | 0004777 | molecular_function | succinate-semialdehyde dehydrogenase (NAD+) activity |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0016620 | molecular_function | oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO A 501 |
| Chain | Residue |
| A | PRO224 |
| A | THR225 |
| A | TYR433 |
| A | HOH835 |
| B | PRO224 |
| B | THR225 |
| B | TYR433 |
| site_id | AC2 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE EDO A 502 |
| Chain | Residue |
| A | PRO424 |
| A | PHE425 |
| A | GLY426 |
| A | ARG435 |
| B | ALA448 |
| B | THR450 |
| A | GLY409 |
| A | ALA410 |
| site_id | AC3 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE EDO A 503 |
| Chain | Residue |
| A | GLU167 |
| A | GLU171 |
| A | PHE175 |
| A | PRO176 |
| A | VAL179 |
| A | PHE180 |
| A | HOH616 |
| A | HOH622 |
| A | HOH706 |
| site_id | AC4 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO A 504 |
| Chain | Residue |
| A | ASP312 |
| A | GLN316 |
| A | GLU359 |
| A | LEU360 |
| A | PHE361 |
| A | EDO509 |
| A | HOH866 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO A 505 |
| Chain | Residue |
| A | GLU99 |
| A | GLN100 |
| A | GLN192 |
| A | HOH623 |
| A | HOH885 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO A 506 |
| Chain | Residue |
| A | PRO22 |
| A | ARG48 |
| A | GLU96 |
| A | SER188 |
| A | GLN189 |
| A | HOH757 |
| site_id | AC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO A 507 |
| Chain | Residue |
| A | GLU208 |
| A | LEU229 |
| A | GLY230 |
| A | GLU359 |
| A | HOH653 |
| site_id | AC8 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE EDO A 508 |
| Chain | Residue |
| A | LEU124 |
| A | PRO143 |
| A | ALA144 |
| A | ASN149 |
| A | GLY441 |
| A | ILE442 |
| A | THR444 |
| A | PHE445 |
| A | HOH671 |
| site_id | AC9 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO A 509 |
| Chain | Residue |
| A | GLU359 |
| A | PHE361 |
| A | EDO504 |
| A | HOH866 |
| site_id | BC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO A 510 |
| Chain | Residue |
| A | MET256 |
| A | SER261 |
| A | ILE263 |
| A | MET416 |
| site_id | BC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO A 511 |
| Chain | Residue |
| A | HIS155 |
| A | ALA156 |
| A | ALA163 |
| A | LEU183 |
| A | LEU184 |
| A | ILE185 |
| site_id | BC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO A 512 |
| Chain | Residue |
| A | GLN319 |
| A | ALA320 |
| A | LYS354 |
| A | ILE355 |
| A | HOH677 |
| site_id | BC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO A 513 |
| Chain | Residue |
| A | ARG267 |
| A | LEU356 |
| A | GLN357 |
| A | LEU379 |
| A | ASP382 |
| site_id | BC5 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE EDO A 514 |
| Chain | Residue |
| A | PHE44 |
| A | ARG47 |
| A | LEU102 |
| A | TYR118 |
| A | PRO120 |
| A | ALA147 |
| A | EDO515 |
| A | EDO516 |
| site_id | BC6 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE EDO A 515 |
| Chain | Residue |
| A | ARG40 |
| A | PRO120 |
| A | EDO514 |
| site_id | BC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO A 516 |
| Chain | Residue |
| A | THR42 |
| A | PHE44 |
| A | ARG47 |
| A | EDO514 |
| A | HOH678 |
| site_id | BC8 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO A 517 |
| Chain | Residue |
| A | SER213 |
| A | LEU214 |
| A | ALA187 |
| A | VAL190 |
| A | ALA210 |
| site_id | BC9 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE PO4 A 518 |
| Chain | Residue |
| A | LYS154 |
| A | ALA156 |
| A | SER157 |
| A | ALA187 |
| A | HOH693 |
| site_id | CC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO B 501 |
| Chain | Residue |
| A | SER45 |
| B | GLU34 |
| B | ALA35 |
| B | HOH680 |
| site_id | CC2 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE EDO B 502 |
| Chain | Residue |
| B | GLU167 |
| B | GLU171 |
| B | PHE175 |
| B | PRO176 |
| B | VAL179 |
| B | PHE180 |
| B | HOH626 |
| B | HOH632 |
| B | HOH746 |
| site_id | CC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO B 503 |
| Chain | Residue |
| B | GLU99 |
| B | GLN100 |
| B | GLN192 |
| B | HOH614 |
| B | HOH888 |
| site_id | CC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO B 504 |
| Chain | Residue |
| B | GLN316 |
| B | GLU359 |
| B | LEU360 |
| B | PHE361 |
| B | EDO510 |
| B | HOH851 |
| site_id | CC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO B 505 |
| Chain | Residue |
| A | ILE57 |
| A | ALA172 |
| A | HOH759 |
| B | ILE57 |
| B | ALA172 |
| B | HOH712 |
| site_id | CC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO B 506 |
| Chain | Residue |
| B | PHE132 |
| B | MET256 |
| B | SER261 |
| B | ILE263 |
| B | MET416 |
| B | EDO511 |
| site_id | CC7 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO B 507 |
| Chain | Residue |
| B | PRO22 |
| B | ARG48 |
| B | GLU96 |
| B | SER188 |
| B | GLN189 |
| B | HOH803 |
| site_id | CC8 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO B 508 |
| Chain | Residue |
| B | GLU208 |
| B | LEU229 |
| B | GLY230 |
| B | GLU359 |
| B | HOH640 |
| site_id | CC9 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE EDO B 509 |
| Chain | Residue |
| B | LEU124 |
| B | PRO143 |
| B | ALA144 |
| B | ASN149 |
| B | GLY441 |
| B | ILE442 |
| B | THR444 |
| B | PHE445 |
| B | HOH701 |
| site_id | DC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO B 510 |
| Chain | Residue |
| B | ILE309 |
| B | GLU359 |
| B | PHE361 |
| B | EDO504 |
| B | HOH851 |
| site_id | DC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO B 511 |
| Chain | Residue |
| B | TRP135 |
| B | GLN136 |
| B | CYS262 |
| B | SER419 |
| B | EDO506 |
| B | HOH644 |
| site_id | DC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO B 512 |
| Chain | Residue |
| B | SER288 |
| B | LEU289 |
| B | ASP300 |
| B | HOH707 |
| B | HOH742 |
| B | HOH880 |
| site_id | DC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO B 513 |
| Chain | Residue |
| B | GLN319 |
| B | ALA320 |
| B | ALA353 |
| B | LYS354 |
| B | ILE355 |
| B | HOH714 |
| site_id | DC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO B 514 |
| Chain | Residue |
| B | ALA187 |
| B | ALA210 |
| B | SER213 |
| B | LEU214 |
| B | HOH885 |
| site_id | DC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE PO4 B 515 |
| Chain | Residue |
| B | LYS154 |
| B | ALA156 |
| B | SER157 |
| B | ALA187 |
| B | HOH730 |
| B | HOH885 |
