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4IRH

Auto-inhibited ERG Ets domain

Functional Information from GO Data
ChainGOidnamespacecontents
A0003700molecular_functionDNA-binding transcription factor activity
A0006355biological_processregulation of DNA-templated transcription
A0006357biological_processregulation of transcription by RNA polymerase II
A0043565molecular_functionsequence-specific DNA binding
Functional Information from PROSITE/UniProt
site_idPS00345
Number of Residues9
DetailsETS_DOMAIN_1 Ets-domain signature 1. LWQFLLELL
ChainResidueDetails
ALEU296-LEU304

site_idPS00346
Number of Residues16
DetailsETS_DOMAIN_2 Ets-domain signature 2. KpnMnYDkLSRALRyY
ChainResidueDetails
ALYS340-TYR355

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues80
DetailsDNA_BIND: ETS => ECO:0000255|PROSITE-ProRule:PRU00237
ChainResidueDetails
AALA287-LYS367

227111

PDB entries from 2024-11-06

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