4IRB
Crystal Structure of Vaccinia Virus Uracil DNA Glycosylase Mutant del171-172D4
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003677 | molecular_function | DNA binding |
| A | 0004844 | molecular_function | uracil DNA N-glycosylase activity |
| A | 0006281 | biological_process | DNA repair |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0016799 | molecular_function | hydrolase activity, hydrolyzing N-glycosyl compounds |
| B | 0003677 | molecular_function | DNA binding |
| B | 0004844 | molecular_function | uracil DNA N-glycosylase activity |
| B | 0006281 | biological_process | DNA repair |
| B | 0016787 | molecular_function | hydrolase activity |
| B | 0016799 | molecular_function | hydrolase activity, hydrolyzing N-glycosyl compounds |
| C | 0003677 | molecular_function | DNA binding |
| C | 0004844 | molecular_function | uracil DNA N-glycosylase activity |
| C | 0006281 | biological_process | DNA repair |
| C | 0016787 | molecular_function | hydrolase activity |
| C | 0016799 | molecular_function | hydrolase activity, hydrolyzing N-glycosyl compounds |
| D | 0003677 | molecular_function | DNA binding |
| D | 0004844 | molecular_function | uracil DNA N-glycosylase activity |
| D | 0006281 | biological_process | DNA repair |
| D | 0016787 | molecular_function | hydrolase activity |
| D | 0016799 | molecular_function | hydrolase activity, hydrolyzing N-glycosyl compounds |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 A 301 |
| Chain | Residue |
| A | GLY159 |
| A | LYS160 |
| A | THR161 |
| A | TYR180 |
| A | HIS181 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE GOL A 302 |
| Chain | Residue |
| A | PHE79 |
| A | ASN120 |
| A | HOH433 |
| A | ASP68 |
| A | PRO69 |
| A | TYR70 |
| A | PRO78 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 B 301 |
| Chain | Residue |
| B | GLY159 |
| B | LYS160 |
| B | THR161 |
| B | TYR180 |
| B | HIS181 |
| B | ALA184 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CL B 302 |
| Chain | Residue |
| B | PRO69 |
| B | TYR70 |
| B | PHE79 |
| B | ASN120 |
| B | HOH430 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 C 301 |
| Chain | Residue |
| C | GLY159 |
| C | LYS160 |
| C | THR161 |
| C | GLY179 |
| C | TYR180 |
| C | HIS181 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 D 301 |
| Chain | Residue |
| D | GLY159 |
| D | LYS160 |
| D | THR161 |
| D | TYR180 |
| D | HIS181 |
Functional Information from PROSITE/UniProt
| site_id | PS00130 |
| Number of Residues | 10 |
| Details | U_DNA_GLYCOSYLASE Uracil-DNA glycosylase signature. RVCVcGIDPY |
| Chain | Residue | Details |
| A | ARG61-TYR70 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | ACT_SITE: Proton acceptor => ECO:0000255|PROSITE-ProRule:PRU10072 |
| Chain | Residue | Details |
| A | ASP68 | |
| B | ASP68 | |
| C | ASP68 | |
| D | ASP68 |
