Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0016829 | molecular_function | lyase activity |
| A | 0016833 | molecular_function | oxo-acid-lyase activity |
| A | 0019629 | biological_process | propionate catabolic process, 2-methylcitrate cycle |
| A | 0046421 | molecular_function | methylisocitrate lyase activity |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0003824 | molecular_function | catalytic activity |
| B | 0016829 | molecular_function | lyase activity |
| B | 0016833 | molecular_function | oxo-acid-lyase activity |
| B | 0019629 | biological_process | propionate catabolic process, 2-methylcitrate cycle |
| B | 0046421 | molecular_function | methylisocitrate lyase activity |
| B | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE PYR A 401 |
| Chain | Residue |
| A | TYR51 |
| A | SER53 |
| A | ALA55 |
| A | ASP92 |
| A | ARG162 |
| A | PRO240 |
| A | VAL241 |
| A | HOH515 |
| site_id | AC2 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE PYR A 402 |
| Chain | Residue |
| A | LEU171 |
| A | HOH607 |
| A | HOH671 |
| B | ARG166 |
| B | LEU171 |
| B | GLU199 |
| B | HOH589 |
| A | GLY170 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE PYR A 403 |
| Chain | Residue |
| A | TYR223 |
| A | TYR224 |
| A | GLU228 |
| A | LYS265 |
| A | HOH675 |
| B | GLU228 |
| site_id | AC4 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE PYR A 404 |
| Chain | Residue |
| A | GLU76 |
| A | ARG77 |
| A | ASP80 |
| A | HOH506 |
| A | HOH594 |
| B | GLU76 |
| B | ARG77 |
| B | HOH501 |
| site_id | AC5 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE PYR B 401 |
| Chain | Residue |
| B | TYR51 |
| B | SER53 |
| B | ALA55 |
| B | ASP92 |
| B | ARG162 |
| B | ILE238 |
| B | PRO240 |
| B | HOH506 |
| B | HOH560 |
Functional Information from PROSITE/UniProt
| site_id | PS00161 |
| Number of Residues | 6 |
| Details | ISOCITRATE_LYASE Isocitrate lyase signature. KKCGHL |
| Chain | Residue | Details |
| A | LYS127-LEU132 | |
