4IPI

Crystal Structure of R314A N-acetyl Neuraminic Acid Synthase from Neiserria meningitidis with Malate bound

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0016051	biological_process	carbohydrate biosynthetic process
A	0046872	molecular_function	metal ion binding
A	0047444	molecular_function	N-acylneuraminate-9-phosphate synthase activity
A	0070085	biological_process	glycosylation

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MN A 401

Chain	Residue
A	TYR186
A	HIS215
A	HIS236
A	LMR402
A	HOH669

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site_id	AC2
Number of Residues	17
Details	BINDING SITE FOR RESIDUE LMR A 402

Chain	Residue
A	LYS129
A	GLY131
A	ASN184
A	TYR186
A	HIS215
A	GLU234
A	HIS236
A	MN401
A	HOH561
A	HOH562
A	HOH563
A	HOH669
A	HOH672
A	GLU25
A	LYS53
A	GLN55
A	THR110

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site_id	AC3
Number of Residues	6
Details	BINDING SITE FOR RESIDUE LMR A 403

Chain	Residue
A	SER33
A	LYS35
A	TYR190
A	HOH653
A	HOH696
A	HOH849

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