4IO1
Crystal structure of ribose-5-isomerase A from Francisella Tularensis
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004751 | molecular_function | ribose-5-phosphate isomerase activity |
| A | 0005829 | cellular_component | cytosol |
| A | 0006014 | biological_process | D-ribose metabolic process |
| A | 0006098 | biological_process | pentose-phosphate shunt |
| A | 0009052 | biological_process | pentose-phosphate shunt, non-oxidative branch |
| A | 0016853 | molecular_function | isomerase activity |
| A | 0044281 | biological_process | small molecule metabolic process |
| B | 0004751 | molecular_function | ribose-5-phosphate isomerase activity |
| B | 0005829 | cellular_component | cytosol |
| B | 0006014 | biological_process | D-ribose metabolic process |
| B | 0006098 | biological_process | pentose-phosphate shunt |
| B | 0009052 | biological_process | pentose-phosphate shunt, non-oxidative branch |
| B | 0016853 | molecular_function | isomerase activity |
| B | 0044281 | biological_process | small molecule metabolic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CL A 301 |
| Chain | Residue |
| A | GLY101 |
| A | GLY103 |
| A | ALA104 |
| A | ALA105 |
| A | GLU109 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL A 302 |
| Chain | Residue |
| A | ASN184 |
| A | PRO185 |
| A | LEU186 |
| site_id | AC3 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CL A 303 |
| Chain | Residue |
| A | HOH538 |
| A | ARG146 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE BR A 305 |
| Chain | Residue |
| A | ASN130 |
| A | THR131 |
| A | ASN134 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE PO4 A 306 |
| Chain | Residue |
| A | SER36 |
| A | THR37 |
| A | LYS127 |
| A | HOH532 |
| A | HOH544 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE PG4 A 307 |
| Chain | Residue |
| A | GLU125 |
| A | SER126 |
| A | LYS128 |
| A | HOH469 |
| A | HOH477 |
| site_id | AC7 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CL B 301 |
| Chain | Residue |
| A | MET144 |
| B | LEU76 |
| site_id | AC8 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE CL B 302 |
| Chain | Residue |
| B | ARG146 |
| site_id | AC9 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE BR B 303 |
| Chain | Residue |
| B | LEU180 |
| B | LYS181 |
| site_id | BC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE PO4 B 304 |
| Chain | Residue |
| B | HIS95 |
| B | ASP169 |
| B | GLY171 |
| B | LEU186 |
| site_id | BC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE PO4 B 305 |
| Chain | Residue |
| B | GLY35 |
| B | SER36 |
| B | THR37 |
| B | LYS127 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Proton acceptor","evidences":[{"evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 12 |
| Details | Binding site: {"evidences":[{"evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 6 |
| Details | Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00170","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00170","evidenceCode":"ECO:0000255"},{"source":"Reference","evidenceCode":"ECO:0000269","citation":{"citationType":"submission","publicationDate":"DEC-2009","submissionDatabase":"PDB data bank","title":"Crystal structure of ribose-5-isomerase A.","authoringGroup":["Center for Structural Genomics of Infectious Diseases (CSGID)"],"authors":["Orlikowska M.","Rostankowski R.","Nakka C.","Hattne J.","Grimshaw S.","Borek D.","Otwinowski Z."]}},{"source":"Reference","evidenceCode":"ECO:0000269","citation":{"citationType":"submission","publicationDate":"JAN-2013","submissionDatabase":"PDB data bank","title":"Structural and biophysical studies of Ribose-5-Phosphate Isomerase A from Francisella tularensis.","authoringGroup":["Center for Structural Genomics of Infectious Diseases (CSGID)"],"authors":["Rostankowski R.","Orlikowska M.","Nakka C.","Grimshaw S.","Borek D.","Otwinowski Z."]}}]} |
| Chain | Residue | Details |
