4IO1
Crystal structure of ribose-5-isomerase A from Francisella Tularensis
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004751 | molecular_function | ribose-5-phosphate isomerase activity |
| A | 0005829 | cellular_component | cytosol |
| A | 0006014 | biological_process | D-ribose metabolic process |
| A | 0006098 | biological_process | pentose-phosphate shunt |
| A | 0009052 | biological_process | pentose-phosphate shunt, non-oxidative branch |
| A | 0016853 | molecular_function | isomerase activity |
| A | 0044281 | biological_process | small molecule metabolic process |
| B | 0004751 | molecular_function | ribose-5-phosphate isomerase activity |
| B | 0005829 | cellular_component | cytosol |
| B | 0006014 | biological_process | D-ribose metabolic process |
| B | 0006098 | biological_process | pentose-phosphate shunt |
| B | 0009052 | biological_process | pentose-phosphate shunt, non-oxidative branch |
| B | 0016853 | molecular_function | isomerase activity |
| B | 0044281 | biological_process | small molecule metabolic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CL A 301 |
| Chain | Residue |
| A | GLY101 |
| A | GLY103 |
| A | ALA104 |
| A | ALA105 |
| A | GLU109 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL A 302 |
| Chain | Residue |
| A | ASN184 |
| A | PRO185 |
| A | LEU186 |
| site_id | AC3 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CL A 303 |
| Chain | Residue |
| A | HOH538 |
| A | ARG146 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE BR A 305 |
| Chain | Residue |
| A | ASN130 |
| A | THR131 |
| A | ASN134 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE PO4 A 306 |
| Chain | Residue |
| A | SER36 |
| A | THR37 |
| A | LYS127 |
| A | HOH532 |
| A | HOH544 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE PG4 A 307 |
| Chain | Residue |
| A | GLU125 |
| A | SER126 |
| A | LYS128 |
| A | HOH469 |
| A | HOH477 |
| site_id | AC7 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CL B 301 |
| Chain | Residue |
| A | MET144 |
| B | LEU76 |
| site_id | AC8 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE CL B 302 |
| Chain | Residue |
| B | ARG146 |
| site_id | AC9 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE BR B 303 |
| Chain | Residue |
| B | LEU180 |
| B | LYS181 |
| site_id | BC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE PO4 B 304 |
| Chain | Residue |
| B | HIS95 |
| B | ASP169 |
| B | GLY171 |
| B | LEU186 |
| site_id | BC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE PO4 B 305 |
| Chain | Residue |
| B | GLY35 |
| B | SER36 |
| B | THR37 |
| B | LYS127 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | ACT_SITE: Proton acceptor => ECO:0000305 |
| Chain | Residue | Details |
| A | GLU109 | |
| B | GLU109 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | BINDING: BINDING => ECO:0000305 |
| Chain | Residue | Details |
| A | THR34 | |
| A | LYS100 | |
| B | THR34 | |
| B | LYS100 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_00170 |
| Chain | Residue | Details |
| A | ASP87 | |
| B | ASP87 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_00170, ECO:0000269|Ref.2, ECO:0000269|Ref.3 |
| Chain | Residue | Details |
| A | LYS127 | |
| B | LYS127 |
