4IMQ
Structural Basis of Substrate Specificity and Protease Inhibition in Norwalk Virus
Functional Information from GO Data
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SCN A 201 |
| Chain | Residue |
| A | PRO2 |
| A | THR4 |
| A | LEU5 |
| A | ARG8 |
| A | HOH404 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE NA A 202 |
| Chain | Residue |
| A | LEU121 |
| A | THR134 |
| A | GLY164 |
| A | HOH503 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SCN A 203 |
| Chain | Residue |
| A | HIS50 |
| A | GLN172 |
| A | ALA173 |
| A | HOH390 |
| site_id | AC4 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR CHAIN B OF PEPTIDE INHIBITOR |
| Chain | Residue |
| A | HIS30 |
| A | ILE109 |
| A | GLN110 |
| A | THR134 |
| A | ILE135 |
| A | PRO136 |
| A | CYS139 |
| A | HIS157 |
| A | ALA158 |
| A | ALA159 |
| A | ALA160 |
| A | GLU181 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 3 |
| Details | Active site: {"description":"For 3CLpro activity","evidences":[{"source":"PROSITE-ProRule","id":"PRU00870","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"16641296","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"23365454","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
