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4ILE

Structure of human ADP-ribosylation factor-like 8A binding to GDP

Functional Information from GO Data
ChainGOidnamespacecontents
A0000166molecular_functionnucleotide binding
A0003924molecular_functionGTPase activity
A0005515molecular_functionprotein binding
A0005525molecular_functionGTP binding
A0005737cellular_componentcytoplasm
A0005764cellular_componentlysosome
A0005765cellular_componentlysosomal membrane
A0005768cellular_componentendosome
A0005819cellular_componentspindle
A0005856cellular_componentcytoskeleton
A0005886cellular_componentplasma membrane
A0007049biological_processcell cycle
A0007059biological_processchromosome segregation
A0008089biological_processanterograde axonal transport
A0015031biological_processprotein transport
A0016020cellular_componentmembrane
A0030424cellular_componentaxon
A0030496cellular_componentmidbody
A0031902cellular_componentlate endosome membrane
A0035577cellular_componentazurophil granule membrane
A0042995cellular_componentcell projection
A0043014molecular_functionalpha-tubulin binding
A0045202cellular_componentsynapse
A0048487molecular_functionbeta-tubulin binding
A0051233cellular_componentspindle midzone
A0051301biological_processcell division
A0070062cellular_componentextracellular exosome
A0101003cellular_componentficolin-1-rich granule membrane
A1904115cellular_componentaxon cytoplasm
Functional Information from PDB Data
site_idAC1
Number of Residues17
DetailsBINDING SITE FOR RESIDUE GDP A 201
ChainResidue
ATYR30
AASP133
ALEU134
ASER163
ACYS164
ALYS165
AHOH301
AHOH342
AHOH351
ASER31
AGLY32
ALYS33
ATHR34
ATHR35
AGLU102
AASN130
ALYS131

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues18
DetailsINTRAMEM: Note=Mediates targeting to membranes => ECO:0000250
ChainResidueDetails
AMSE1-GLU19

site_idSWS_FT_FI2
Number of Residues2
DetailsBINDING:
ChainResidueDetails
AGLN29
AASN130

site_idSWS_FT_FI3
Number of Residues1
DetailsBINDING: BINDING => ECO:0000250
ChainResidueDetails
AASP71

218853

PDB entries from 2024-04-24

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