4IKZ
Crystal structure of peptide transporter POT (E310Q mutant) in complex with alafosfalin
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005886 | cellular_component | plasma membrane |
| A | 0006857 | biological_process | oligopeptide transport |
| A | 0015333 | molecular_function | peptide:proton symporter activity |
| A | 0015833 | biological_process | peptide transport |
| A | 0016020 | cellular_component | membrane |
| A | 0022857 | molecular_function | transmembrane transporter activity |
| A | 0035442 | biological_process | dipeptide transmembrane transport |
| A | 0035443 | biological_process | tripeptide transmembrane transport |
| A | 0042937 | molecular_function | tripeptide transmembrane transporter activity |
| A | 0055085 | biological_process | transmembrane transport |
| A | 0071916 | molecular_function | dipeptide transmembrane transporter activity |
| A | 1902600 | biological_process | proton transmembrane transport |
| A | 1904680 | molecular_function | peptide transmembrane transporter activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 A 601 |
| Chain | Residue |
| A | ARG16 |
| A | GLY17 |
| A | PHE19 |
| A | GLY20 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 A 602 |
| Chain | Residue |
| A | PRO14 |
| A | GLN15 |
| A | ARG16 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 A 603 |
| Chain | Residue |
| A | HOH723 |
| A | ARG487 |
| A | ARG490 |
| site_id | AC4 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE SO4 A 604 |
| Chain | Residue |
| A | HIS390 |
| A | THR464 |
| site_id | AC5 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE SO4 A 606 |
| Chain | Residue |
| A | ARG289 |
| A | GLY395 |
| site_id | AC6 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE AFS A 607 |
| Chain | Residue |
| A | ARG36 |
| A | TYR40 |
| A | ARG43 |
| A | TYR78 |
| A | ALA169 |
| A | GLN309 |
| A | GLN310 |
| A | ASN342 |
| A | PRO343 |
| A | HOH747 |
Functional Information from PROSITE/UniProt
| site_id | PS01022 |
| Number of Residues | 25 |
| Details | PTR2_1 PTR2 family proton/oligopeptide symporters signature 1. GGWLADrVFGtsrAVfygGlLimaG |
| Chain | Residue | Details |
| A | GLY84-GLY108 |
| site_id | PS01023 |
| Number of Residues | 13 |
| Details | PTR2_2 PTR2 family proton/oligopeptide symporters signature 2. FsiFYMgINLGAF |
| Chain | Residue | Details |
| A | PHE158-PHE170 |
