4IJH
Fragment-based Discovery of Protein-Protein Interaction Inhibitors of Replication Protein A
Functional Information from GO Data
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE 1EJ A 201 |
| Chain | Residue |
| A | ARG31 |
| A | VAL93 |
| A | 1EJ202 |
| A | 1EJ203 |
| A | 1EJ204 |
| A | 1EJ205 |
| A | ILE33 |
| A | THR34 |
| A | ARG43 |
| A | SER55 |
| A | MET57 |
| A | LEU87 |
| A | ASP89 |
| A | ARG91 |
| site_id | AC2 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE 1EJ A 202 |
| Chain | Residue |
| A | HIS0 |
| A | ARG7 |
| A | ASN85 |
| A | ARG91 |
| A | 1EJ201 |
| A | 1EJ203 |
| A | 1EJ204 |
| A | 1EJ205 |
| A | HOH315 |
| A | HOH327 |
| site_id | AC3 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE 1EJ A 203 |
| Chain | Residue |
| A | ARG41 |
| A | ALA59 |
| A | THR60 |
| A | ILE83 |
| A | ILE95 |
| A | MET97 |
| A | 1EJ201 |
| A | 1EJ202 |
| A | 1EJ204 |
| A | 1EJ205 |
| A | HOH382 |
| site_id | AC4 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE 1EJ A 204 |
| Chain | Residue |
| A | ARG41 |
| A | MET57 |
| A | LEU87 |
| A | LYS88 |
| A | VAL93 |
| A | 1EJ201 |
| A | 1EJ202 |
| A | 1EJ203 |
| A | 1EJ205 |
| A | HOH309 |
| A | HOH380 |
| site_id | AC5 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE 1EJ A 205 |
| Chain | Residue |
| A | ARG7 |
| A | ARG41 |
| A | ARG43 |
| A | ASN85 |
| A | THR86 |
| A | ARG91 |
| A | ILE95 |
| A | 1EJ201 |
| A | 1EJ202 |
| A | 1EJ203 |
| A | 1EJ204 |
| A | HOH349 |
| A | HOH370 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"N-acetylmethionine","evidences":[{"source":"PubMed","id":"19413330","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"22223895","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 3 |
| Details | Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)","evidences":[{"source":"PubMed","id":"26474068","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
