4IHB

X-RAY STRUCTURE OF THE canonical C2A DOMAIN FROM HUMAN DYSFERLIN

Functional Information from PDB Data

site_id	AC1
Number of Residues	7
Details	BINDING SITE FOR RESIDUE FMT A 201

Chain	Residue
A	PHE28
A	ALA29
A	GLU64
A	HOH308
A	HOH309
A	HOH310
F	GLY56

---

site_id	AC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE FMT A 202

Chain	Residue
A	GLN120
A	HOH327
A	SER98
A	ALA99

---

site_id	AC3
Number of Residues	2
Details	BINDING SITE FOR RESIDUE FMT A 203

Chain	Residue
A	ARG34
A	PHE50

---

site_id	AC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE FMT A 204

Chain	Residue
A	LYS36
A	TRP46
A	ASN47
A	HOH319

---

site_id	AC5
Number of Residues	7
Details	BINDING SITE FOR RESIDUE FMT A 205

Chain	Residue
A	TYR8
A	GLU10
A	ASN102
A	VAL118
A	HOH314
B	SER96
B	SER98

---

site_id	AC6
Number of Residues	7
Details	BINDING SITE FOR RESIDUE FMT A 206

Chain	Residue
A	HIS13
A	THR14
A	THR17
A	ASP18
A	ILE19
A	SER20
A	HOH321

---

site_id	AC7
Number of Residues	4
Details	BINDING SITE FOR RESIDUE FMT A 207

Chain	Residue
A	GLY30
A	VAL31
A	LYS32
F	HOH307

---

site_id	AC8
Number of Residues	5
Details	BINDING SITE FOR RESIDUE FMT A 208

Chain	Residue
A	GLN61
A	LEU92
B	ALA84
B	LYS85
B	PRO104

---

site_id	AC9
Number of Residues	5
Details	BINDING SITE FOR RESIDUE FMT B 201

Chain	Residue
B	VAL31
B	LYS33
B	GLU51
B	TRP52
B	ASP53

---

site_id	BC1
Number of Residues	7
Details	BINDING SITE FOR RESIDUE FMT B 202

Chain	Residue
B	PHE28
B	ALA29
B	GLU64
B	HOH312
D	GLY30
D	FMT201
D	HOH308

---

site_id	BC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE FMT B 203

Chain	Residue
B	LYS33
B	GLY49
B	PHE50
B	GLU51
B	HOH344

---

site_id	BC3
Number of Residues	3
Details	BINDING SITE FOR RESIDUE FMT B 204

Chain	Residue
B	LYS33
B	ARG34
B	HOH344

---

site_id	BC4
Number of Residues	6
Details	BINDING SITE FOR RESIDUE FMT B 205

Chain	Residue
A	PRO95
A	LEU97
B	PRO104
B	LEU105
B	GLY114
B	ALA115

---

site_id	BC5
Number of Residues	3
Details	BINDING SITE FOR RESIDUE FMT B 206

Chain	Residue
B	ASN11
B	GLY114
B	SER116

---

site_id	BC6
Number of Residues	5
Details	BINDING SITE FOR RESIDUE FMT B 207

Chain	Residue
A	SER96
A	LEU97
A	SER122
A	TYR123
B	GLU10

---

site_id	BC7
Number of Residues	8
Details	BINDING SITE FOR RESIDUE FMT C 201

Chain	Residue
C	ILE38
C	SER41
C	ASN43
C	PRO44
C	VAL45
C	HOH309
C	HOH332
C	HOH343

---

site_id	BC8
Number of Residues	6
Details	BINDING SITE FOR RESIDUE FMT C 202

Chain	Residue
C	GLY30
C	LYS32
C	HOH329
E	GLY30
E	LYS32
E	FMT203

---

site_id	BC9
Number of Residues	3
Details	BINDING SITE FOR RESIDUE FMT C 203

Chain	Residue
C	GLU90
C	SER100
C	HOH341

---

site_id	CC1
Number of Residues	1
Details	BINDING SITE FOR RESIDUE FMT C 204

Chain	Residue
C	HOH333

---

site_id	CC2
Number of Residues	7
Details	BINDING SITE FOR RESIDUE FMT D 201

Chain	Residue
B	FMT202
B	HOH333
D	GLY30
D	VAL31
D	LYS32
D	HOH308
D	HOH317

---

site_id	CC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE FMT D 202

Chain	Residue
D	LYS33
D	GLU51
D	ASP53
D	HOH309

---

site_id	CC4
Number of Residues	6
Details	BINDING SITE FOR RESIDUE FMT D 203

Chain	Residue
D	LYS33
D	PHE50
D	GLU51
D	FMT207
D	HOH307
D	HOH336

---

site_id	CC5
Number of Residues	4
Details	BINDING SITE FOR RESIDUE FMT D 204

Chain	Residue
D	LYS36
D	TRP46
D	ASN47
D	GLU48

---

site_id	CC6
Number of Residues	2
Details	BINDING SITE FOR RESIDUE FMT D 205

Chain	Residue
E	TRP46
E	ASN47

---

site_id	CC7
Number of Residues	4
Details	BINDING SITE FOR RESIDUE FMT D 206

Chain	Residue
D	VAL31
D	LYS32
D	LYS33
D	FMT208

---

site_id	CC8
Number of Residues	5
Details	BINDING SITE FOR RESIDUE FMT D 207

Chain	Residue
D	LYS33
D	ARG34
D	PHE50
D	FMT203
D	HOH331

---

site_id	CC9
Number of Residues	2
Details	BINDING SITE FOR RESIDUE FMT D 208

Chain	Residue
D	LYS32
D	FMT206

---

site_id	DC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE FMT D 209

Chain	Residue
B	VAL31
D	VAL27
D	HIS66
D	FMT211

---

site_id	DC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE FMT D 210

Chain	Residue
B	GLY56
D	ALA29
D	GLU64
D	FMT211
D	HOH322

---

site_id	DC3
Number of Residues	6
Details	BINDING SITE FOR RESIDUE FMT D 211

Chain	Residue
D	VAL27
D	PHE28
D	ALA29
D	GLY30
D	FMT209
D	FMT210

---

site_id	DC4
Number of Residues	3
Details	BINDING SITE FOR RESIDUE FMT D 212

Chain	Residue
D	ASN102
E	SER98
E	GLN120

---

site_id	DC5
Number of Residues	5
Details	BINDING SITE FOR RESIDUE FMT E 201

Chain	Residue
D	TYR8
D	GLU10
E	SER96
E	SER98
E	SER122

---

site_id	DC6
Number of Residues	5
Details	BINDING SITE FOR RESIDUE FMT E 202

Chain	Residue
E	LYS33
E	ARG34
E	PHE50
E	FMT203
E	FMT204

---

site_id	DC7
Number of Residues	3
Details	BINDING SITE FOR RESIDUE FMT E 203

Chain	Residue
C	FMT202
E	LYS32
E	FMT202

---

site_id	DC8
Number of Residues	3
Details	BINDING SITE FOR RESIDUE FMT E 204

Chain	Residue
E	ARG34
E	GLU48
E	FMT202

---

site_id	DC9
Number of Residues	5
Details	BINDING SITE FOR RESIDUE FMT E 205

Chain	Residue
E	ASN11
E	HIS13
E	THR113
E	HOH305
E	HOH339

---

site_id	EC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE FMT E 206

Chain	Residue
E	ALA84
E	LYS85
E	PRO104
F	ASP60
F	HOH350

---

site_id	EC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CA E 207

Chain	Residue
D	LYS39
E	ASP18
E	ILE19
E	ASP21
E	ASN40
E	HOH340

---

site_id	EC3
Number of Residues	5
Details	BINDING SITE FOR RESIDUE FMT F 201

Chain	Residue
F	SER98
F	ALA99
F	SER100
F	GLN120
F	FMT202

---

site_id	EC4
Number of Residues	5
Details	BINDING SITE FOR RESIDUE FMT F 202

Chain	Residue
F	GLU90
F	ALA99
F	SER100
F	SER100
F	FMT201

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	600
Details	Domain: {"description":"C2 1","evidences":[{"source":"PROSITE-ProRule","id":"PRU00041","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	24
Details	Binding site: {"evidences":[{"source":"PubMed","id":"24239457","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---