4IF7
Mycobacterium Tuberculosis Methionine aminopeptidase Type 1c in complex with homocysteine-methyl disulfide
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004177 | molecular_function | aminopeptidase activity |
| A | 0004239 | molecular_function | initiator methionyl aminopeptidase activity |
| A | 0005506 | molecular_function | iron ion binding |
| A | 0005829 | cellular_component | cytosol |
| A | 0006508 | biological_process | proteolysis |
| A | 0008233 | molecular_function | peptidase activity |
| A | 0016485 | biological_process | protein processing |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0050897 | molecular_function | cobalt ion binding |
| A | 0070006 | molecular_function | metalloaminopeptidase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE CO A 401 |
| Chain | Residue |
| A | ASP142 |
| A | HIS205 |
| A | THR236 |
| A | GLU238 |
| A | GLU269 |
| A | CO402 |
| A | HCM403 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CO A 402 |
| Chain | Residue |
| A | GLU269 |
| A | CO401 |
| A | HCM403 |
| A | ASP131 |
| A | ASP142 |
| site_id | AC3 |
| Number of Residues | 15 |
| Details | BINDING SITE FOR RESIDUE HCM A 403 |
| Chain | Residue |
| A | THR94 |
| A | PHE100 |
| A | HIS114 |
| A | ASP131 |
| A | THR133 |
| A | ASP142 |
| A | HIS205 |
| A | PHE211 |
| A | HIS212 |
| A | GLU238 |
| A | TRP255 |
| A | GLU269 |
| A | CO401 |
| A | CO402 |
| A | HOH564 |
Functional Information from PROSITE/UniProt
| site_id | PS00680 |
| Number of Residues | 19 |
| Details | MAP_1 Methionine aminopeptidase subfamily 1 signature. FtGHGIGttfHnglvVl.HY |
| Chain | Residue | Details |
| A | PHE202-TYR220 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 7 |
| Details | Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_01974","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"15882055","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"20038112","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"21465667","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
