4IEX

unliganded room-temp Cysteine Dioxygenase at pH 6.2

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005506	molecular_function	iron ion binding
A	0005829	cellular_component	cytosol
A	0006534	biological_process	cysteine metabolic process
A	0007595	biological_process	lactation
A	0008198	molecular_function	ferrous iron binding
A	0008270	molecular_function	zinc ion binding
A	0016151	molecular_function	nickel cation binding
A	0016702	molecular_function	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
A	0017172	molecular_function	cysteine dioxygenase activity
A	0019448	biological_process	L-cysteine catabolic process
A	0033762	biological_process	response to glucagon
A	0042412	biological_process	taurine biosynthetic process
A	0043200	biological_process	response to amino acid
A	0045471	biological_process	response to ethanol
A	0046439	biological_process	L-cysteine metabolic process
A	0046872	molecular_function	metal ion binding
A	0051213	molecular_function	dioxygenase activity
A	0051384	biological_process	response to glucocorticoid
A	0051591	biological_process	response to cAMP

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE FE2 A 501

Chain	Residue
A	HIS86
A	HIS88
A	HIS140
A	HOH601

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	3
Details	BINDING: BINDING => ECO:0000269|PubMed:16611640

Chain	Residue	Details
A	HIS86
A	HIS88
A	HIS140

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site_id	SWS_FT_FI2
Number of Residues	2
Details	CROSSLNK: 3'-(S-cysteinyl)-tyrosine (Cys-Tyr) => ECO:0000269|PubMed:16611640

Chain	Residue	Details
A	CYS93
A	TYR157

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